Literature summary extracted from

Prokhorova, I.V.; Osterman, I.A.; Burakovsky, D.E.; Serebryakova, M.V.; Galyamina, M.A.; Pobeguts, O.V.; Altukhov, I.; Kovalchuk, S.; Alexeev, D.G.; Govorun, V.M.; Bogdanov, A.A.; Sergiev, P.V.; Dontsova, O.A.
Modified nucleotides m2G966/m5C967 of Escherichia coli 16S rRNA are required for attenuation of tryptophan operon (2013), Sci. Rep., 3, 3236.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.1.1.176	S-adenosyl-L-methionine + cytosine967 in 16S rRNA	Escherichia coli	-	S-adenosyl-L-homocysteine + 5-methylcytosine967 in 16S rRNA	-	?
2.1.1.176	S-adenosyl-L-methionine + cytosine967 in 16S rRNA	Escherichia coli BW25113	-	S-adenosyl-L-homocysteine + 5-methylcytosine967 in 16S rRNA	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.176	Escherichia coli	-	-	-
2.1.1.176	Escherichia coli BW25113	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.176	S-adenosyl-L-methionine + cytosine967 in 16S rRNA	-	Escherichia coli	S-adenosyl-L-homocysteine + 5-methylcytosine967 in 16S rRNA	-	?
2.1.1.176	S-adenosyl-L-methionine + cytosine967 in 16S rRNA	-	Escherichia coli BW25113	S-adenosyl-L-homocysteine + 5-methylcytosine967 in 16S rRNA	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.1.176	rsmB	-	Escherichia coli

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Release 2026.1 (March 2026)