Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Smith, K.; Zeng, X.; Lin, J.
    Discovery of bile salt hydrolase inhibitors using an efficient high-throughput screening system (2014), PLoS ONE, 9, e85344.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.24 caffeic acid phenethyl ester 99.7% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 carnosic acid 96.8% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 cephradine
-
 Ligilactobacillus salivarius
3.5.1.24 chrysophanol 3.7% inhibition at 1.25 mM Ligilactobacillus salivarius
3.5.1.24 Cloxacillin
-
 Ligilactobacillus salivarius
3.5.1.24 demeclocycline 92.0% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 doxycycline 92.9% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 epicatechin monogallate 98.6% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 erythromycin 36.5% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 gossypetin 97.3% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 Lincomycin 67.3% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 menadione 87.2% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 methacycline 90.2% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 additional information identification of bile salt hydrolase inhibitors using an efficient high-throughput screening system, method optimization, overview; no inhibition by folic acid at 1.5 mM and bacitracin at 5 mM Ligilactobacillus salivarius
3.5.1.24 oxytetracycline 97.4% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 purpurogallin 83.0% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 riboflavin 99.3% inhibition at 1 mM Ligilactobacillus salivarius
3.5.1.24 roxarsone 98.4% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 streptomycin
-
 Ligilactobacillus salivarius
3.5.1.24 sulfamethazine 48.7% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 theaflavanin 18.1% inhibition at 5 mM Ligilactobacillus salivarius
3.5.1.24 tylosin 23.8% inhibition at 5 mM Ligilactobacillus salivarius

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.24 Ligilactobacillus salivarius
-
 isolated from chicken
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.24 glycocholic acid + H2O
-
 Ligilactobacillus salivarius cholate + glycine
-
 ?
3.5.1.24 taurodeoxycholic acid + H2O
-
 Ligilactobacillus salivarius deoxycholate + taurine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.24 bile salt hydrolase
-
 Ligilactobacillus salivarius
3.5.1.24 BSH
-
 Ligilactobacillus salivarius

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.5.1.24 37
-
 assay at Ligilactobacillus salivarius

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.1.24 6
-
 assay at Ligilactobacillus salivarius