Literature summary extracted from

Zhu, Y.P.; Peng, Z.G.; Wu, Z.Y.; Li, J.R.; Huang, M.H.; Si, S.Y.; Jiang, J.D.
Host APOBEC3G protein inhibits HCV replication through direct binding at NS3 (2015), PLoS ONE, 10, e0121608.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.5.4.B9	cytosine in single-stranded viral DNA + H2O	Homo sapiens	-	uracil in single-stranded viral DNA + NH3	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.4.B9	Homo sapiens	Q9HC16	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.5.4.B9	Huh-7.5 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.5.4.B9	cytosine in single-stranded viral DNA + H2O	-	Homo sapiens	uracil in single-stranded viral DNA + NH3	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.5.4.B9	A3G	-	Homo sapiens
3.5.4.B9	APOBEC3G	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
3.5.4.B9	physiological function	APOBEC3G protein inhibits HCV replication through direct binding at non-structural protein NS3 at its C-terminus, which is responsible for NS3's helicase and NTPase activities	Homo sapiens

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Release 2023.1 (January 2023)