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Literature summary extracted from

  • Haziza, S.; Magnani, R.; Lan, D.; Keinan, O.; Saada, A.; Hershkovitz, E.; Yanay, N.; Cohen, Y.; Nevo, Y.; Houtz, R.L.; Sheffield, V.C.; Golan, H.; Parvari, R.
    Calmodulin methyltransferase is required for growth, muscle strength, somatosensory development and brain function (2015), PLoS Genet., 11, e1005388.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.60 S-adenosyl-L-methionine + calmodulin L-lysine Mus musculus
-
 S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.60 Mus musculus Q3U2J5
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.60 brain
-
 Mus musculus
-
2.1.1.60 kidney
-
 Mus musculus
-
2.1.1.60 liver
-
 Mus musculus
-
2.1.1.60 muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.60 S-adenosyl-L-methionine + calmodulin L-lysine
-
 Mus musculus S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.60 calmodulin lysine methyl transferase
-
 Mus musculus
2.1.1.60 CaM KMT
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.1.1.60 malfunction enzyme-deficient mice have deficits in motor learning, complex coordination and learning of aversive stimuli Mus musculus
2.1.1.60 physiological function the enzyme is essential for normal body growth and somatosensory development, as well as for the proper functioning of the adult mouse brain Mus musculus