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Literature summary extracted from

  • Sayanova, O.; Haslam, R.; Caleron, M.; Napier, J.
    Cloning and characterization of unusual fatty acid desaturases from Anemone leveillei: Identification of an acyl-coenzyme A C20 DELTA5-desaturase responsible for the synthesis of sciadonic acid (2007), Plant Physiol., 144, 455-467.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.30 expressed in Arabidopsis thaliana Anemone leveillei
1.14.19.37 expressed in Arabidopsis thaliana Anemone leveillei

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.37 (11Z,14Z)-icosa-11,14-dienoyl-CoA + reduced acceptor + O2 Anemone leveillei
-
 (5Z,11Z,14Z)-icosa-5,11,14-trienoyl-CoA + acceptor + H2O
-
 ?
1.14.19.37 (11Z,14Z,17Z)-icosa-11,14,17-trienoyl-CoA + reduced acceptor + O2 Anemone leveillei
-
 (5Z,11Z,14Z,17Z)-icosa-5,11,14,17-tetraenoyl-CoA + acceptor + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.30 Anemone leveillei
-
-
-
1.14.19.37 Anemone leveillei
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.19.30 seed
-
 Anemone leveillei
-
1.14.19.37 seed
-
 Anemone leveillei
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.30 eicosa-11,14,17-trienoyl-CoA + acceptor + O2 + H+
-
 Anemone leveillei eicosa-5,11,14,17-tetraenoyl-CoA + ? i.e. juniperoyl-CoA ?
1.14.19.30 eicosa-11,14-dienoyl-CoA + acceptor + O2 + H+
-
 Anemone leveillei eicosa-5,11,14-trienoyl-CoA + ? i.e. sciadonoyl-CoA ?
1.14.19.37 (11Z,14Z)-icosa-11,14-dienoyl-CoA + reduced acceptor + O2
-
 Anemone leveillei (5Z,11Z,14Z)-icosa-5,11,14-trienoyl-CoA + acceptor + H2O
-
 ?
1.14.19.37 (11Z,14Z,17Z)-icosa-11,14,17-trienoyl-CoA + reduced acceptor + O2
-
 Anemone leveillei (5Z,11Z,14Z,17Z)-icosa-5,11,14,17-tetraenoyl-CoA + acceptor + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.30 AL21
-
 Anemone leveillei
1.14.19.30 C20 DELTA5cis-desaturase
-
 Anemone leveillei
1.14.19.30 DELTA5-desaturase
-
 Anemone leveillei
1.14.19.37 acyl-coenzyme A C20 DELTA5-desaturase
-
 Anemone leveillei
1.14.19.37 AL10
-
 Anemone leveillei
1.14.19.37 AL21
-
 Anemone leveillei
1.14.19.37 C20 DELTA5cis-desaturase
-
 Anemone leveillei

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.30 additional information the enzyme does not contain a cytochrome b5 domain Anemone leveillei
1.14.19.37 additional information does not contain a cytochrome b5 domain Anemone leveillei

General Information

EC Number General Information Comment Organism
1.14.19.37 metabolism the enzyme is required for the synthesis of sciadonic acid and juniperonic acid Anemone leveillei