Literature summary extracted from

Morant, M.; Jorgensen, K.; Schaller, H.; Pinot, F.; Moller, B.L.; Werck-Reichhart, D.; Bak, S.
CYP703 is an ancient cytochrome P450 in land plants catalyzing in-chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis in pollen (2007), Plant Cell, 19, 1473-1487.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.14.14.130	expressed in Saccharomyces cerevisiae strain WAT1	Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.14.130	dodecanoate + [reduced NADPH-hemoprotein reductase] + O2	Arabidopsis thaliana	-	7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.14.130	Arabidopsis thaliana	Q9LNJ4	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.14.130	anther	developinmg anther	Arabidopsis thaliana	-
1.14.14.130	bud	-	Arabidopsis thaliana	-
1.14.14.130	flower	developing flower	Arabidopsis thaliana	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.14.130	dodecanoate + [reduced NADPH-hemoprotein reductase] + O2	-	Arabidopsis thaliana	7-hydroxydodecanoate + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.14.130	CYP703A2	-	Arabidopsis thaliana

General Information

EC Number	General Information	Comment	Organism
1.14.14.130	malfunction	Arabidopsis CYP703A2 knockout lines show impaired pollen development and a partial male-sterile phenotype through impaired pollen wall development with absence of exine	Arabidopsis thaliana
1.14.14.130	physiological function	the enzyme provides building blocks for sporopollenin synthesis in pollen	Arabidopsis thaliana

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Release 2023.1 (January 2023)