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Literature summary extracted from

  • Huang, Y.S.; Chaudhary, S.; Thurmond, J.M.; Bobik, E.G.; Yuan, L.; Chan, G.M.; Kirchner, S.J.; Mukerji, P.; Knutzon, D.S.
    Cloning of DELAT12- and DELTA6-desaturases from Mortierella alpina and recombinant production of gamma-linolenic acid in Saccharomyces cerevisiae (1999), Lipids, 34, 649-659.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.47 expressed in Saccharomyces cerevisiae Mortierella alpina

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.47 alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Mortierella alpina
-
 stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
1.14.19.47 linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Mortierella alpina
-
 gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.47 Mortierella alpina Q9UVV3
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.47 alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Mortierella alpina stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
1.14.19.47 linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Mortierella alpina gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.47 DELTA6-desaturase
-
 Mortierella alpina
1.14.19.47 DES6
-
 Mortierella alpina

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.47 cytochrome b5
-
 Mortierella alpina