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Literature summary extracted from
- The effect of dietary polyenylphosphatidylcholine on microsomal delta-6-desaturase activity, fatty acid composition, and microviscosity in rat liver under oxidative stress (1993), J. Nutr. Biochem., 4, 690-694.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.14.19.47 | microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.19.47 | alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ | Rattus norvegicus | - |
stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O | - |
? |  |
| 1.14.19.47 | linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ | Rattus norvegicus | - |
gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.19.47 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.19.47 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.19.47 | alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ | - |
Rattus norvegicus | stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O | - |
? | |
| 1.14.19.47 | linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ | - |
Rattus norvegicus | gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.19.47 | D6D | - |
Rattus norvegicus |
| 1.14.19.47 | DELTA-6-desaturase | - |
Rattus norvegicus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.19.47 | cytochrome b5 | - |
Rattus norvegicus |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 1.14.19.47 | Rattus norvegicus | after adriamycin treatment, enzyme activity increases in polyenylphosphatidylcholine-fed and trilinolein-fed rats | up |
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Release 2023.1 (January 2023)
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