EC Number | Cloned (Comment) | Organism |
---|---|---|
7.2.2.10 | expressed in Escherichia coli BL21(DE3) cells | Bombyx mori |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
7.2.2.10 | thapsigargin | - |
Bombyx mori |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
7.2.2.10 | sarcoplasmic reticulum | - |
Bombyx mori | 16529 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.2.2.10 | ATP + H2O + Ca2+[side 1] | Bombyx mori | - |
ADP + phosphate + Ca2+[side 2] | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
7.2.2.10 | Bombyx mori | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
7.2.2.10 | silk gland | - |
Bombyx mori | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
7.2.2.10 | ATP + H2O + Ca2+[side 1] | - |
Bombyx mori | ADP + phosphate + Ca2+[side 2] | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
7.2.2.10 | sarcoplasmic reticulum Ca2+-ATPase | - |
Bombyx mori |
7.2.2.10 | SERCA | - |
Bombyx mori |
EC Number | General Information | Comment | Organism |
---|---|---|---|
7.2.2.10 | malfunction | after injection of thapsigargin to block enzyme activity, silkworms show a silk-spinning deficiency (30% of silkworms cannot spin normally and another 25% constructes abnormal cocoons) and their cocoons have higher calcium content compared to that of controls | Bombyx mori |
7.2.2.10 | physiological function | the enzyme has a key function in calcium transportation in anterior silk gland that is related to maintaining a suitable ionic environment. This ionic environment with a proper Ca2+ concentration is crucial for the formation of silk fibers with favorable mechanical performances | Bombyx mori |