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Literature summary extracted from

  • Doshi, R.; Van Veen, H.
    Substrate binding stabilizes a pre-translocation intermediate in the ATP-binding cassette transport protein MsbA (2013), J. Biol. Chem., 288, 21638-21647.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.5.2.6 expressed in Escherichia coli XL1 Blue cells Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.5.2.6 ATP + H2O + Lipid A/in Escherichia coli
-
 ADP + phosphate + Lipid A/out
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.5.2.6 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.5.2.6 Ni2+ affinity resin column chromatography Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.5.2.6 ATP + H2O + DMSO/in
-
 Escherichia coli ADP + phosphate + DMSO/out
-
 ?
7.5.2.6 ATP + H2O + ethidium/in
-
 Escherichia coli ADP + phosphate + ethidium/out
-
 ?
7.5.2.6 ATP + H2O + Hoechst 33342
-
 Escherichia coli ADP + phosphate + Hoechst 33342/out
-
 ?
7.5.2.6 ATP + H2O + Lipid A/in
-
 Escherichia coli ADP + phosphate + Lipid A/out
-
 ?
7.5.2.6 ATP + H2O + verapamil/in
-
 Escherichia coli ADP + phosphate + verapamil/out
-
 ?

Subunits

EC Number Subunits Comment Organism
7.5.2.6 homodimer 2 * about 50000, SDS-PAGE Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
7.5.2.6 MsbA
-
 Escherichia coli