Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Li, J.; Attila, C.; Wang, L.; Wood, T.K.; Valdes, J.J.; Bentley, W.E.
    Quorum sensing in Escherichia coli is signaled by AI-2/LsrR: effects on small RNA and biofilm architecture (2007), J. Bacteriol., 189, 6011-6020.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.189 gene lsrK Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.189 additional information genomic deletion of gene lsrK. Genes lsrK and lsrR knockouts behave identically concerning the quantity and architecture of biofilms by affecting genes including flu and wza, small riboregulators respond to the QS regulators lsrR and lsrK, e.g. the sRNA cell division inhibitor DicF is induced by at least twofold in both lsrR and lsrK mutants. 117 and 32 genes are induced and repressed, respectively, by lsrK, transcriptosome analysis in enzyme mutants, overview Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.189 Mg2+ required Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.189 ATP + autoinducer-2 Escherichia coli i.e. AI-2 ADP + phosphorylated autoinducer-2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.189 Escherichia coli
-
 W3110, gene lsrK
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.189 ATP + autoinducer-2 i.e. AI-2 Escherichia coli ADP + phosphorylated autoinducer-2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.189 lsrK
-
 Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.189 ATP
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
2.7.1.189 malfunction deletion of lsrR and lsrK does not affect growth or motility. Genomic deletion of gene lsrK. Genes lsrK and lsrR knockouts behave identically concerning the quantity and architecture of biofilms by affecting genes including flu and wza, small riboregulators respond to the QS regulators lsrR and lsrK Escherichia coli
2.7.1.189 metabolism the regulatory network for the uptake of Escherichia coli autoinducer 2 (AI-2) is comprised of a transporter complex, LsrABCD, its repressor, LsrR, and the cognate signal kinase, LsrK. This network is an integral part of the AI-2 quorum-sensing system, extended model for AI-2 signaling, overview Escherichia coli
2.7.1.189 physiological function repressor LsrR and kinase LsrK directly regulate autoinducer 2, AI-2, uptake. Small riboregulators respond to the QS regulators lsrR and lsrK. 117 and 32 genes are induced and repressed, respectively, by lsrK Escherichia coli