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Literature summary extracted from

  • Peng, K.; Zheng, C.; Xue, J.; Chen, X.; Yang, W.; Liu, J.; Bai, W.; Li, H.
    Delta 5 fatty acid desaturase upregulates the synthesis of polyunsaturated fatty acids in the marine diatom Phaeodactylum tricornutum (2014), J. Agric. Food Chem., 62, 8773-8776.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.30 overexpressed in Phaeodactylum tricornutum Phaeodactylum tricornutum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.30 (8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Phaeodactylum tricornutum
-
 (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
1.14.19.30 (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Phaeodactylum tricornutum
-
 (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.30 Phaeodactylum tricornutum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.30 (8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Phaeodactylum tricornutum (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
1.14.19.30 (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Phaeodactylum tricornutum (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.30 D5b
-
 Phaeodactylum tricornutum
1.14.19.30 delta 5 desaturase
-
 Phaeodactylum tricornutum
1.14.19.30 DELTA 5 fatty acid desaturase
-
 Phaeodactylum tricornutum

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.30 cytochrome b5
-
 Phaeodactylum tricornutum

General Information

EC Number General Information Comment Organism
1.14.19.30 metabolism delta 5 desaturase plays a role in the eicosapentaenoic acid biosynthetic pathway Phaeodactylum tricornutum