EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.14.19.17 | myristic acid | the activity of wild-type isoform DES1 is linearly increased in the presence of increased concentrations of myristic acid. The dihydroceramide DELTA4-desaturase activity of the myristoylable enzyme is reproducibly and significantly higher than the unmyristoylated enzyme | Rattus norvegicus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.19.17 | expressed in in Cos-7 cells | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.14.19.17 | 40000 | - |
x * 40000, V5-His-tagged fusion protein, SDS-PAGE | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.19.17 | dihydroceramide + ferrocytochrome b5 + O2 + H+ | Rattus norvegicus | - |
(4E)-sphing-4-enine ceramide + ferricytochrome b5 + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.19.17 | Rattus norvegicus | Q5XIF5 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.19.17 | dihydroceramide + ferrocytochrome b5 + O2 + H+ | - |
Rattus norvegicus | (4E)-sphing-4-enine ceramide + ferricytochrome b5 + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.14.19.17 | ? | x * 40000, V5-His-tagged fusion protein, SDS-PAGE | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.19.17 | Degs1 | isoform | Rattus norvegicus |
1.14.19.17 | dihydroceramide DELTA4-desaturase 1 | - |
Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.19.17 | cytochrome b5 | - |
Rattus norvegicus |