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Literature summary extracted from

  • Jiang, L.; Bechtel, M.D.; Bean, J.L.; Winefield, R.; Williams, T.D.; Zaidi, A.; Michaelis, E.K.; Michaelis, M.L.
    Effects of gangliosides on the activity of the plasma membrane Ca2+-ATPase (2014), Biochim. Biophys. Acta, 1838, 1255-1265.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.2.2.10 Calmodulin
-
 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.10 D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol
-
 Rattus norvegicus
7.2.2.10 neuraminidase
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.2.2.10 plasma membrane
-
 Rattus norvegicus 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.2.2.10 ATP + H2O + Ca2+[side 1] Rattus norvegicus
-
 ADP + phosphate + Ca2+[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.10 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.10 brain
-
 Rattus norvegicus
-
7.2.2.10 neuron
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.10 ATP + H2O + Ca2+[side 1]
-
 Rattus norvegicus ADP + phosphate + Ca2+[side 2]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.2.2.10 plasma membrane Ca2+-ATPase
-
 Rattus norvegicus
7.2.2.10 PMCA
-
 Rattus norvegicus

General Information

EC Number General Information Comment Organism
7.2.2.10 malfunction age-associated loss in PMCA activity results in part from changes in the lipid environment of this Ca2+ transporter Rattus norvegicus