Literature summary extracted from

Hertlein, T.; Sturm, V.; Lorenz, U.; Sumathy, K.; Jakob, P.; Ohlsen, K.
Bioluminescence and 19F magnetic resonance imaging visualize the efficacy of lysostaphin alone and in combination with oxacillin against Staphylococcus aureus in murine thigh and catheter-associated infection models (2014), Antimicrob. Agents Chemother., 58, 1630-1638.

Application

EC Number	Application	Comment	Organism
3.4.24.75	medicine	lysostaphin exerts high levels of activity against antibiotic-resistant strains of Staphylococcus aureus	Staphylococcus simulans

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.4.24.75	expressed as mature lysostaphin free from preprolysostaphin and prolysostaphin in Escherichia coli	Staphylococcus simulans

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
3.4.24.75	Zn2+	zinc metalloprotease	Staphylococcus simulans

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.4.24.75	peptidoglycan + H2O	Staphylococcus simulans	-	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.75	Staphylococcus simulans	P10547	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.24.75	peptidoglycan + H2O	-	Staphylococcus simulans	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.24.75	r-lysostaphin	-	Staphylococcus simulans

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Release 2023.1 (January 2023)