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Literature summary extracted from
- Acrosin activity regulation by protein kinase C and tyrosine kinase in bovine sperm acrosome exocytosis induced by lysophosphatidylcholine (2012), Reprod. Domest. Anim., 47, 915-920.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.10 | lysophosphatidylcholine | in heparin-capacitated spermatozoa, the addition of lysophosphatidylcholine produces a significant increase (about 7fold) in acrosin activity | Bos taurus |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.10 | proacrosin + H2O | Bos taurus | - |
acrosin + ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.10 | Bos taurus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.10 | spermatozoon | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.10 | Nalpha-benzoyl-DL-arginine 4-nitroanilide + H2O | - |
Bos taurus | Nalpha-benzoyl-DL-arginine + 4-nitroaniline | - |
? | |
| 3.4.21.10 | proacrosin + H2O | - |
Bos taurus | acrosin + ? | - |
? | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.21.10 | physiological function | the enzyme is capable of hydrolysing the zona pellucida in bovine oocytes | Bos taurus |
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Release 2023.1 (January 2023)
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