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Literature summary extracted from

  • Sun, Y.; Wang, X.; Yuan, S.; Dang, M.; Li, X.; Zhang, X.C.; Rao, Z.
    An open conformation determined by a structural switch for 2A protease from coxsackievirus A16 (2013), Protein Cell, 4, 782-792.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.29 expressed in Escherichia coli Coxsackievirus A16

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.29 EDTA the enzyme is slightly inhibited by 10 mM EDTA Coxsackievirus A16

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.22.29 Zn2+ contains zinc Coxsackievirus A16

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.29 eukaryotic translation initiation factor 4G I + H2O Coxsackievirus A16
-
 ?
-
 ?
3.4.22.29 eukaryotic translation initiation factor 4G II + H2O Coxsackievirus A16
-
 ?
-
 ?
3.4.22.29 thrombin + H2O Coxsackievirus A16
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.29 Coxsackievirus A16 Q9QF31
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.29 HiTrap Q column chromatography Coxsackievirus A16

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.29 eukaryotic translation initiation factor 4G I + H2O
-
 Coxsackievirus A16 ?
-
 ?
3.4.22.29 eukaryotic translation initiation factor 4G II + H2O
-
 Coxsackievirus A16 ?
-
 ?
3.4.22.29 thrombin + H2O
-
 Coxsackievirus A16 ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.22.29 hexamer x-ray crystallography Coxsackievirus A16

Synonyms

EC Number Synonyms Comment Organism
3.4.22.29 2A protease
-
 Coxsackievirus A16
3.4.22.29 2Apro
-
 Coxsackievirus A16