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Literature summary extracted from

  • Prakash, A.; Doublie, S.; Wallace, S.S.
    The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage (2012), Prog. Mol. Biol. Transl. Sci., 110, 71-91.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.2.23 DNA containing 8-oxoguanine residues + H2O Lactococcus lactis best substrate DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing 8-oxoguanine residues + H2O Escherichia coli best substrate DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing 8-oxoguanine residues + H2O Geobacillus stearothermophilus best substrate DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing 8-oxoguanine residues + H2O Thermus thermophilus best substrate DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing 8-oxoguanine residues + H2O Thermus thermophilus DSM 579 best substrate DNA + 8-oxoguanine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.23 Escherichia coli P05523
-
-
3.2.2.23 Geobacillus stearothermophilus P84131
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-
3.2.2.23 Lactococcus lactis P42371
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-
3.2.2.23 Thermus thermophilus O50606
-
-
3.2.2.23 Thermus thermophilus DSM 579 O50606
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-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.2.23 DNA containing 8-oxoguanine residues + H2O best substrate Lactococcus lactis DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing 8-oxoguanine residues + H2O best substrate Escherichia coli DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing 8-oxoguanine residues + H2O best substrate Geobacillus stearothermophilus DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing 8-oxoguanine residues + H2O best substrate Thermus thermophilus DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing 8-oxoguanine residues + H2O best substrate Thermus thermophilus DSM 579 DNA + 8-oxoguanine
-
 ?
3.2.2.23 DNA containing formamidopyrimidine-guanine residues + H2O
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 Lactococcus lactis 4,6-diamino-5-formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing formamidopyrimidine-guanine residues + H2O
-
 Escherichia coli 4,6-diamino-5-formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing formamidopyrimidine-guanine residues + H2O
-
 Geobacillus stearothermophilus 4,6-diamino-5-formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing formamidopyrimidine-guanine residues + H2O
-
 Thermus thermophilus 4,6-diamino-5-formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing formamidopyrimidine-guanine residues + H2O
-
 Thermus thermophilus DSM 579 4,6-diamino-5-formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing methylated formamidopyrimidine-guanine residues + H2O
-
 Lactococcus lactis 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing methylated formamidopyrimidine-guanine residues + H2O
-
 Escherichia coli 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing methylated formamidopyrimidine-guanine residues + H2O
-
 Geobacillus stearothermophilus 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing methylated formamidopyrimidine-guanine residues + H2O
-
 Thermus thermophilus 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + DNA
-
 ?
3.2.2.23 DNA containing methylated formamidopyrimidine-guanine residues + H2O
-
 Thermus thermophilus DSM 579 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + DNA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.2.23 formamidopyrimidine DNA glycosylase
-
 Lactococcus lactis
3.2.2.23 formamidopyrimidine DNA glycosylase
-
 Escherichia coli
3.2.2.23 formamidopyrimidine DNA glycosylase
-
 Geobacillus stearothermophilus
3.2.2.23 formamidopyrimidine DNA glycosylase
-
 Thermus thermophilus
3.2.2.23 FPG
-
 Lactococcus lactis
3.2.2.23 FPG
-
 Escherichia coli
3.2.2.23 FPG
-
 Geobacillus stearothermophilus
3.2.2.23 FPG
-
 Thermus thermophilus