Literature summary extracted from

Lu, N.; Shen, Q.; Mahoney, T.R.; Neukomm, L.J.; Wang, Y.; Zhou, Z.
Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells (2012), PLoS Biol., 10, e1001245.

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.3.64	Caenorhabditis elegans	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.3.64	embryo	-	Caenorhabditis elegans	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.1.3.64	MTM-1	-	Caenorhabditis elegans

General Information

EC Number	General Information	Comment	Organism
3.1.3.64	malfunction	inactivating mtm-1, blocks phagosome maturation	Caenorhabditis elegans
3.1.3.64	physiological function	MTM-1 antagonizes the activities of piki-1 (PI 3-kinase) and vps-34 (PI 3-kinase) on phagosomes	Caenorhabditis elegans
3.1.3.64	physiological function	MTM-1 down-regulates phagosomal PtdIns(3)P, this is demonstrated in mtm-1 mutant embryos where the level of the PtdIns(3)P on phagosomes is significantly higher than in wild-type embryos	Caenorhabditis elegans

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Release 2023.1 (January 2023)