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Literature summary extracted from
- Purification of NAD+ glycohydrolase from human serum (2013), Oncol. Lett., 6, 227-231.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.2.2.6 | extracellular | surface antigen CD38 | Homo sapiens | - |
- |
| 3.2.2.6 | soluble | - |
Homo sapiens | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.2.2.6 | 38000 | - |
gel filtration | Homo sapiens |
| 3.2.2.6 | 39000 | - |
1 * 39000, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.2.6 | cyclic ADP-ribose + H2O | Homo sapiens | - |
ADP-D-ribose | - |
? |  |
| 3.2.2.6 | NAD+ | Homo sapiens | - |
cyclic ADP-ribose + nicotinamide | - |
? | |
| 3.2.2.6 | NAD+ + H2O | Homo sapiens | overall reaction | ADP-D-ribose + nicotinamide | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.2.6 | Homo sapiens | P28907 | - |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.2.2.6 | native enzyme 480fold from serum by ammonium sulfate fractionation, affinity chromatography, gel filtration, and isoelectric focusing, and again gel filtration, to homogeneity | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.2.6 | blood serum | surface antigen CD38 | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.2.6 | cyclic ADP-ribose + H2O | - |
Homo sapiens | ADP-D-ribose | - |
? | |
| 3.2.2.6 | NAD+ | - |
Homo sapiens | cyclic ADP-ribose + nicotinamide | - |
? | |
| 3.2.2.6 | NAD+ + H2O | overall reaction | Homo sapiens | ADP-D-ribose + nicotinamide | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.2.2.6 | monomer | 1 * 39000, SDS-PAGE | Homo sapiens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.2.2.6 | CD38 | - |
Homo sapiens |
| 3.2.2.6 | NAD+ glycohydrolase | - |
Homo sapiens |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 3.2.2.6 | Homo sapiens | isoelectric focusing | 6.6 | 6.4 |
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Release 2023.1 (January 2023)
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