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Literature summary extracted from
- Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function (2014), Mol. Biol. Cell, 25, 1836-1844.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.17.24 | Danio rerio | Q68EI3 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.17.24 | ciliary body | - |
Danio rerio | - |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.4.17.24 | physiological function | isoform ccp5 knockdown increases cilia tubulin glutamylation, induces ciliopathy phenotypes, including axis curvature, hydrocephalus, and pronephric cysts, and disrupts multicilia motility. ccp5 knockdown restores tubulin glutamylation and promotes multicilia assembly in intraflagellar transport-deficient zebrafish | Danio rerio |
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Release 2023.1 (January 2023)
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