Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Carroll, R.K.; Robison, T.M.; Rivera, F.E.; Davenport, J.E.; Jonsson, I.M.; Florczyk, D.; Tarkowski, A.; Potempa, J.; Koziel, J.; Shaw, L.N.
    Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus (2012), Microbes Infect., 14, 989-999.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.1 intracellular
-
 Staphylococcus aureus 5622
-
3.4.11.10 cytosol
-
 Staphylococcus aureus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.1 Staphylococcus aureus
-
-
-
3.4.11.10 Staphylococcus aureus
-
-
-

Synonyms

EC Number Synonyms Comment Organism
3.4.11.1 LAP
-
 Staphylococcus aureus
3.4.11.1 pepZ
-
 Staphylococcus aureus
3.4.11.10 LAP
-
 Staphylococcus aureus
3.4.11.10 leucine aminopeptidase
-
 Staphylococcus aureus
3.4.11.10 pepZ
-
 Staphylococcus aureus

Expression

EC Number Organism Comment Expression
3.4.11.1 Staphylococcus aureus gene expression analysis shows that pepZ expression is highest in the intracellular environment up

General Information

EC Number General Information Comment Organism
3.4.11.1 malfunction disruption of the pepZ gene results in an attenuation of virulence in both localized and systemic models of infection Staphylococcus aureus
3.4.11.1 physiological function LAP is required for survival inside human macrophages Staphylococcus aureus