EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.51 | (2E)-2-{4-[(3-oxido-2,1,3-benzoxadiazol-5-yl)methoxy]benzylidene}hydrazinecarboximidamide | - |
Trypanosoma cruzi | |
3.4.22.51 | (3-oxido-2,1,3-benzoxadiazol-5-yl)methyl (2E)-2-(4-hydroxybenzylidene)hydrazinecarbimidothioate | - |
Trypanosoma cruzi | |
3.4.22.51 | (m-bromophenyl)ethylketone thiosemicarbazone | - |
Trypanosoma cruzi | |
3.4.22.51 | 2,2-dimethyl-5-[4-(N-phenyl-N'-phenylethyl)amidinopiperazin-1-ylmethyl]-2H-benzimidazole 1,3-di-N-oxide | - |
Trypanosoma cruzi | |
3.4.22.51 | 5-[4-(N,N'-diphenyl)amidinopiperazin-1-ylmethyl]benzo[1,2-c]1,2,5-oxadiazole N-oxide | - |
Trypanosoma cruzi | |
3.4.22.51 | 5-[4-(N-benzyl-N'-phenyl)amidinopiperazin-1-ylmethyl]-2,2-dimethyl-2H-benzimidazole 1,3-di-N-oxide | - |
Trypanosoma cruzi | |
3.4.22.51 | 5-[4-(N-benzyl-N'-phenyl)amidinopiperazin-1-ylmethyl]benzo[1,2-c]1,2,5-oxadiazole N-oxide | - |
Trypanosoma cruzi | |
3.4.22.51 | 5-[4-(N-furyl-N'-phenyl)amidinopiperazin-1-ylmethyl]-2,2-dimethyl-2H-benzimidazole 1,3-di-N-oxide | - |
Trypanosoma cruzi | |
3.4.22.51 | 5-[4-(N-furyl-N'-phenyl)amidinopiperazin-1-ylmethyl]benzo[1,2-c]1,2,5-oxadiazole N-oxide | - |
Trypanosoma cruzi | |
3.4.22.51 | 5-[4-(N-phenyl-N'-phenylethyl)amidinopiperazin-1-yl methyl]benzo[1,2-c]1,2,5-oxadiazole N-oxide | - |
Trypanosoma cruzi | |
3.4.22.51 | 6-[(E)-2-(phenylsulfonyl)ethenyl]-2,1,3-benzoxadiazole 1-oxide | - |
Trypanosoma cruzi | |
3.4.22.51 | Amphotericin B | - |
Trypanosoma cruzi | |
3.4.22.51 | Bnz | - |
Trypanosoma cruzi | |
3.4.22.51 | E-64 | - |
Trypanosoma cruzi | |
3.4.22.51 | additional information | 0.01% (v/v) of Triton X-100 does not interfere with enzyme activity | Trypanosoma cruzi | |
3.4.22.51 | N'-(furan-2-ylmethyl)-N-phenylpiperazine-1-carboximidamide | 10% inhibition at 0.1 mM, at pH 5.3, temperature not specified in the publication | Trypanosoma cruzi | |
3.4.22.51 | N'-benzyl-N-phenylpiperazine-1-carboximidamide | 5.4% inhibition at 0.1 mM, at pH 5.3, temperature not specified in the publication | Trypanosoma cruzi | |
3.4.22.51 | N,N'-diphenylpiperazine-1-carboximidamide | 6.3% inhibition at 0.1 mM, at pH 5.3, temperature not specified in the publication | Trypanosoma cruzi | |
3.4.22.51 | N-phenyl-N'-(2-phenylethyl)piperazine-1-carboximidamide | 3.2% inhibition at 0.1 mM, at pH 5.3, temperature not specified in the publication | Trypanosoma cruzi | |
3.4.22.51 | Nfx | - |
Trypanosoma cruzi | |
3.4.22.51 | Triton X-100 | non-specific inhibition in the presence of 0.02% (v/v) Triton X-100 | Trypanosoma cruzi | |
3.4.22.51 | VS4 | - |
Trypanosoma cruzi |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.51 | Hemoglobin + H2O | Trypanosoma cruzi | - |
? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.51 | Trypanosoma cruzi | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.51 | Hemoglobin + H2O | - |
Trypanosoma cruzi | ? | - |
? | |
3.4.22.51 | Z-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Trypanosoma cruzi | Z-Phe-Arg + 7-amino-4-methylcoumarin | - |
? |