EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.99.50 | - |
Mycolicibacterium smegmatis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.99.50 | EDTA | - |
Mycolicibacterium smegmatis |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.99.50 | Fe2+ | requires Fe2+ for activity | Mycolicibacterium smegmatis |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.5.1.118 | 24139 | - |
x * 24139, calculated from sequence | Mycolicibacterium smegmatis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.99.50 | hercynine + gamma-L-glutamyl-L-cysteine + O2 | Mycolicibacterium smegmatis | the enzyme is part of the biosynthesis pathway of ergothioneine | gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O | - |
? | |
3.5.1.118 | S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O | Mycolicibacterium smegmatis | the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria | S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate | - |
? | |
3.5.1.118 | S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O | Mycolicibacterium smegmatis ATCC 700084 | the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria | S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.99.50 | Mycolicibacterium smegmatis | A0R5N0 | - |
- |
3.5.1.118 | Mycolicibacterium smegmatis | A0R5M9 | - |
- |
3.5.1.118 | Mycolicibacterium smegmatis ATCC 700084 | A0R5M9 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.99.50 | hercynine + gamma-L-glutamyl-L-cysteine + O2 | the enzyme is part of the biosynthesis pathway of ergothioneine | Mycolicibacterium smegmatis | gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O | - |
? | |
1.14.99.50 | hercynine + gamma-L-glutamyl-L-cysteine + O2 | hercynine i.e. Nalpha,Nalpha,Nalpha-trimethyl-L-histidine. The enzyme is specific for both hercynine and gamma-L-glutamyl-L-cysteine. No activity with cysteine, N-acetylcysteine, or glutathione | Mycolicibacterium smegmatis | gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide + H2O | - |
? | |
3.5.1.118 | S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O | - |
Mycolicibacterium smegmatis | S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate | - |
? | |
3.5.1.118 | S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O | the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria | Mycolicibacterium smegmatis | S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate | - |
? | |
3.5.1.118 | S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O | - |
Mycolicibacterium smegmatis ATCC 700084 | S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate | - |
? | |
3.5.1.118 | S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O | the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria | Mycolicibacterium smegmatis ATCC 700084 | S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.5.1.118 | ? | x * 24139, calculated from sequence | Mycolicibacterium smegmatis |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.99.50 | EgtB | - |
Mycolicibacterium smegmatis |
3.5.1.118 | EgtC | - |
Mycolicibacterium smegmatis |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.14.99.50 | 7.6 | - |
assay at | Mycolicibacterium smegmatis |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.99.50 | metabolism | the enzyme is part of the biosynthesis pathway of ergothioneine | Mycolicibacterium smegmatis |
3.5.1.118 | metabolism | the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria | Mycolicibacterium smegmatis |