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Literature summary extracted from
- Angiotensin-converting enzyme inhibitory effects by plant phenolic compounds: a study of structure activity relationships (2013), J. Agric. Food Chem., 61, 11832-11839.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.15.1 | 4-coumaric acid | - |
Oryctolagus |  |
| 3.4.15.1 | 4-coumaric acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | 4-hydroxybenzoic acid | - |
Oryctolagus | |
| 3.4.15.1 | 4-hydroxybenzoic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | apigenin | - |
Oryctolagus | |
| 3.4.15.1 | apigenin | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | benzoic acid | - |
Oryctolagus | |
| 3.4.15.1 | benzoic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | caffeic acid | - |
Oryctolagus | |
| 3.4.15.1 | caffeic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | catechol | - |
Oryctolagus | |
| 3.4.15.1 | catechol | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | ellagic acid | - |
Oryctolagus | |
| 3.4.15.1 | ellagic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | epicatechin | - |
Oryctolagus | |
| 3.4.15.1 | epicatechin | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | ferulic acid | - |
Oryctolagus | |
| 3.4.15.1 | ferulic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | gallic acid | - |
Oryctolagus | |
| 3.4.15.1 | gallic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | kaempferol | - |
Oryctolagus | |
| 3.4.15.1 | kaempferol | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | phloretin | - |
Oryctolagus | |
| 3.4.15.1 | phloretin | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | protocatechuic acid | - |
Oryctolagus | |
| 3.4.15.1 | protocatechuic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | pyrogallol | - |
Oryctolagus | |
| 3.4.15.1 | pyrogallol | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | quercetin | - |
Oryctolagus | |
| 3.4.15.1 | quercetin | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | resveratrol | - |
Oryctolagus | |
| 3.4.15.1 | resveratrol | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | rutin | - |
Oryctolagus | |
| 3.4.15.1 | rutin | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | syringic acid | - |
Oryctolagus | |
| 3.4.15.1 | syringic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | Tannic acid | - |
Oryctolagus | |
| 3.4.15.1 | Tannic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | trans-cinnamic acid | - |
Oryctolagus | |
| 3.4.15.1 | trans-cinnamic acid | - |
Oryctolagus cuniculus | |
| 3.4.15.1 | vanillic acid | - |
Oryctolagus | |
| 3.4.15.1 | vanillic acid | - |
Oryctolagus cuniculus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.15.1 | Oryctolagus | - |
- |
- |
| 3.4.15.1 | Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.15.1 | lung | - |
Oryctolagus cuniculus | - |
| 3.4.15.1 | lung | - |
Oryctolagus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.15.1 | hippuryl-His-Leu + H2O | - |
Oryctolagus | hippuric acid + His-Leu | - |
? | |
| 3.4.15.1 | hippuryl-L-His-L-Leu + H2O | - |
Oryctolagus cuniculus | hippuric acid + L-His-L-Leu | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.15.1 | ACE | - |
Oryctolagus cuniculus |
| 3.4.15.1 | ACE | - |
Oryctolagus |
| 3.4.15.1 | angiotensin-converting enzyme | - |
Oryctolagus cuniculus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.15.1 | 37 | - |
assay at | Oryctolagus cuniculus |
| 3.4.15.1 | 37 | - |
assay at | Oryctolagus |
IC50 Value
| EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|---|
| 3.4.15.1 | 0.23 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | Tannic acid | |
| 3.4.15.1 | 0.23 | - |
pH not specified in the publication, 37°C | Oryctolagus | Tannic acid | |
| 3.4.15.1 | 0.415 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | quercetin | |
| 3.4.15.1 | 0.415 | - |
pH not specified in the publication, 37°C | Oryctolagus | quercetin | |
| 3.4.15.1 | 0.472 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | rutin | |
| 3.4.15.1 | 0.472 | - |
pH not specified in the publication, 37°C | Oryctolagus | rutin | |
| 3.4.15.1 | 0.512 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | kaempferol | |
| 3.4.15.1 | 0.512 | - |
pH not specified in the publication, 37°C | Oryctolagus | kaempferol | |
| 3.4.15.1 | 0.667 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | apigenin | |
| 3.4.15.1 | 0.667 | - |
pH not specified in the publication, 37°C | Oryctolagus | apigenin | |
| 3.4.15.1 | 0.97 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | resveratrol | |
| 3.4.15.1 | 0.97 | - |
pH not specified in the publication, 37°C | Oryctolagus | resveratrol | |
| 3.4.15.1 | 1.1 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | phloretin | |
| 3.4.15.1 | 1.1 | - |
pH not specified in the publication, 37°C | Oryctolagus | phloretin | |
| 3.4.15.1 | 1.12 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | pyrogallol | |
| 3.4.15.1 | 1.12 | - |
pH not specified in the publication, 37°C | Oryctolagus | pyrogallol | |
| 3.4.15.1 | 1.381 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | epicatechin | |
| 3.4.15.1 | 1.381 | - |
pH not specified in the publication, 37°C | Oryctolagus | epicatechin | |
| 3.4.15.1 | 2 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | ellagic acid | |
| 3.4.15.1 | 2 | - |
pH not specified in the publication, 37°C | Oryctolagus | ellagic acid | |
| 3.4.15.1 | 2.1 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | caffeic acid | |
| 3.4.15.1 | 2.1 | - |
pH not specified in the publication, 37°C | Oryctolagus | caffeic acid | |
| 3.4.15.1 | 2.8 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | 4-coumaric acid | |
| 3.4.15.1 | 2.8 | - |
pH not specified in the publication, 37°C | Oryctolagus | 4-coumaric acid | |
| 3.4.15.1 | 3.7 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | gallic acid | |
| 3.4.15.1 | 3.7 | - |
pH not specified in the publication, 37°C | Oryctolagus | gallic acid | |
| 3.4.15.1 | 4.4 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | ferulic acid | |
| 3.4.15.1 | 4.4 | - |
pH not specified in the publication, 37°C | Oryctolagus | ferulic acid | |
| 3.4.15.1 | 5.07 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | protocatechuic acid | |
| 3.4.15.1 | 5.07 | - |
pH not specified in the publication, 37°C | Oryctolagus | protocatechuic acid | |
| 3.4.15.1 | 5.95 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | 4-hydroxybenzoic acid | |
| 3.4.15.1 | 5.95 | - |
pH not specified in the publication, 37°C | Oryctolagus | 4-hydroxybenzoic acid | |
| 3.4.15.1 | 6.2 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | benzoic acid | |
| 3.4.15.1 | 6.2 | - |
pH not specified in the publication, 37°C | Oryctolagus | benzoic acid | |
| 3.4.15.1 | 7.7 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | catechol | |
| 3.4.15.1 | 7.7 | - |
pH not specified in the publication, 37°C | Oryctolagus | catechol | |
| 3.4.15.1 | 8 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | vanillic acid | |
| 3.4.15.1 | 8 | - |
pH not specified in the publication, 37°C | Oryctolagus | vanillic acid | |
| 3.4.15.1 | 8.5 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | trans-cinnamic acid | |
| 3.4.15.1 | 8.5 | - |
pH not specified in the publication, 37°C | Oryctolagus | trans-cinnamic acid | |
| 3.4.15.1 | 9.3 | - |
37°C, pH not specified in the publication | Oryctolagus cuniculus | syringic acid | |
| 3.4.15.1 | 9.3 | - |
pH not specified in the publication, 37°C | Oryctolagus | syringic acid | |
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