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Literature summary extracted from

  • Darewicz, M.; Borawska, J.; Vegarud, G.E.; Minkiewicz, P.; Iwaniak, A.
    Angiotensin I-converting enzyme (ACE) inhibitory activity and ACE inhibitory peptides of salmon (Salmo salar) protein hydrolysates obtained by human and porcine gastrointestinal enzymes (2014), Int. J. Mol. Sci., 15, 14077-14101.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 Ala-Leu-Pro-His-Ala
-
 Homo sapiens
3.4.15.1 Ile-Trp
-
 Homo sapiens
3.4.15.1 Ile-Trp-His-His-Thr
-
 Homo sapiens
3.4.15.1 Ile-Tyr
-
 Homo sapiens
3.4.15.1 Ile-Val-Tyr
-
 Homo sapiens
3.4.15.1 Thr-Val-Tyr
-
 Homo sapiens
3.4.15.1 Tyr-Ala-Leu-Pro-His-Ala
-
 Homo sapiens
3.4.15.1 Val-Phe-Pro-Ser
-
 Homo sapiens
3.4.15.1 Val-Thr-Val-Asn-Pro-Tyr-Lys-Trp-Leu-Pro
-
 Homo sapiens
3.4.15.1 Val-Trp
-
 Homo sapiens
3.4.15.1 Val-Tyr
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 hippuryl-L-His-L-Leu + H2O
-
 Homo sapiens hippuric acid + L-His-L-Leu
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.15.1 ACE
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.15.1 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.15.1 8.2
-
 assay at Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.4.15.1 0.00046
-
 pH 8.2, 37°C Homo sapiens Val-Phe-Pro-Ser
3.4.15.1 0.00048
-
 pH 8.2, 37°C Homo sapiens Ile-Val-Tyr
3.4.15.1 0.0014
-
 pH 8.2, 37°C Homo sapiens Val-Trp
3.4.15.1 0.0021
-
 pH 8.2, 37°C Homo sapiens Ile-Tyr
3.4.15.1 0.0047
-
 pH 8.2, 37°C Homo sapiens Ile-Trp
3.4.15.1 0.0055
-
 pH 8.2, 37°C Homo sapiens Val-Thr-Val-Asn-Pro-Tyr-Lys-Trp-Leu-Pro
3.4.15.1 0.0058
-
 pH 8.2, 37°C Homo sapiens Ile-Trp-His-His-Thr
3.4.15.1 0.0071
-
 pH 8.2, 37°C Homo sapiens Val-Tyr
3.4.15.1 0.0098
-
 pH 8.2, 37°C Homo sapiens Tyr-Ala-Leu-Pro-His-Ala
3.4.15.1 0.01
-
 pH 8.2, 37°C Homo sapiens Ala-Leu-Pro-His-Ala
3.4.15.1 0.015
-
 pH 8.2, 37°C Homo sapiens Thr-Val-Tyr