Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Vakifahmetoglu-Norberg, H.; Norberg, E.; Perdomo, A.B.; Olsson, M.; Ciccosanti, F.; Orrenius, S.; Fimia, G.M.; Piacentini, M.; Zhivotovsky, B.
    Caspase-2 promotes cytoskeleton protein degradation during apoptotic cell death (2013), Cell Death Dis., 4, e940.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.55 ankyrin specific caspase-2 inhibitor Homo sapiens
3.4.22.55 benzyloxycarbonyl-Val-Asp-Val-Ala-Asp-fluoromethylketone
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.55 cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.55 all-spectrin + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 BID + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 CUX1 + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 cyclophilin A + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 desmoplakin + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 DNp63a + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 fatty acid binding protein 5 + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 golgin-160 + H2O Homo sapiens caspase-2-specific substrate ?
-
 ?
3.4.22.55 HDAC4 + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 huntingtin + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 ICAD + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 MDM-2 + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 myotrophin + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 PARP + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 plakin + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 profilin 1 + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 protein kinase Cdelta + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 PRP31 pre-mRNA processing factor 31 homolog + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 Rho kinase-2 + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 soluble superoxide dismutase 1 + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 stathmin 1 + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 thioredoxin + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 tropomyosin 2beta + H2O Homo sapiens
-
 ?
-
 ?
3.4.22.55 tropomyosin 3 + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.55 Homo sapiens P42575
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.55 HCT-116 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.55 all-spectrin + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 BID + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 CUX1 + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 cyclophilin A + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 desmoplakin + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 DNp63a + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 fatty acid binding protein 5 + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 golgin-160 + H2O caspase-2-specific substrate Homo sapiens ?
-
 ?
3.4.22.55 HDAC4 + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 huntingtin + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 ICAD + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 MDM-2 + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 additional information no activity with N-acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin Homo sapiens ?
-
 ?
3.4.22.55 myotrophin + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 N-acetyl-Val-Asp-Val-Ala-Asp-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens N-acetyl-Val-Asp-Val-Ala-Asp + 7-amino-4-methylcoumarin
-
 ?
3.4.22.55 PARP + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 plakin + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 profilin 1 + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 protein kinase Cdelta + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 PRP31 pre-mRNA processing factor 31 homolog + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 Rho kinase-2 + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 soluble superoxide dismutase 1 + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 stathmin 1 + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 thioredoxin + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 tropomyosin 2beta + H2O
-
 Homo sapiens ?
-
 ?
3.4.22.55 tropomyosin 3 + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.22.55 CASP-2
-
 Homo sapiens