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Literature summary extracted from
- Enzymatic and molecular characterisation of leucine aminopeptidase of Burkholderia pseudomallei (2013), BMC Microbiol., 13, 110.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.1 | 1,10-phenanthroline | - |
Burkholderia pseudomallei |  |
| 3.4.11.1 | amastatin | - |
Burkholderia pseudomallei | |
| 3.4.11.1 | EDTA | - |
Burkholderia pseudomallei | |
| 3.4.11.1 | PMSF | - |
Burkholderia pseudomallei | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.1 | Ca2+ | enhances activity | Burkholderia pseudomallei | |
| 3.4.11.1 | K+ | enhances activity | Burkholderia pseudomallei | |
| 3.4.11.1 | Mg2+ | enhances activity | Burkholderia pseudomallei | |
| 3.4.11.1 | Mn2+ | inhibits activity | Burkholderia pseudomallei | |
| 3.4.11.1 | Na+ | enhances activity | Burkholderia pseudomallei | |
| 3.4.11.1 | Zn2+ | inhibits activity | Burkholderia pseudomallei | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | 52700 | - |
calculated from cDNA | Burkholderia pseudomallei |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.1 | Burkholderia pseudomallei | - |
- |
- |
| 3.4.11.1 | Burkholderia pseudomallei NCTC 13178 | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.1 | L-Leu-4-nitroanilide + H2O | - |
Burkholderia pseudomallei | L-Leu + 4-nitroaniline | - |
? | |
| 3.4.11.1 | L-Leu-4-nitroanilide + H2O | - |
Burkholderia pseudomallei NCTC 13178 | L-Leu + 4-nitroaniline | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.11.1 | LAP | - |
Burkholderia pseudomallei |
| 3.4.11.1 | leucine aminopeptidase | - |
Burkholderia pseudomallei |
| 3.4.11.1 | PepA | - |
Burkholderia pseudomallei |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | 37 | - |
assay at | Burkholderia pseudomallei |
| 3.4.11.1 | 50 | - |
optimal temperature | Burkholderia pseudomallei |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | 9 | - |
- |
Burkholderia pseudomallei |
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Release 2023.1 (January 2023)
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