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Literature summary extracted from

  • Shihadih, D.S.; Harris, T.R.; Yang, J.; Merzlikin, O.; Lee, K.S.; Hammock, B.D.; Morisseau, C.
    Identification of potent inhibitors of the chicken soluble epoxide hydrolase (2015), Bioorg. Med. Chem. Lett., 25, 276-279.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.3.2.10 1-[4-[4-(hydroxymethyl)phenoxy]cyclohexyl]-3-tricyclo[3.3.1.13,7]dec-1-ylurea
-
 Gallus gallus
3.3.2.10 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid
-
 Gallus gallus
3.3.2.10 methyl 4-[[4-([[4-(trifluoromethoxy)phenyl]carbamoyl]amino)piperidin-1-yl]carbonyl]benzoate
-
 Gallus gallus
3.3.2.10 N-methyl-4-([4-[(tricyclo[3.3.1.13,7]dec-1-ylcarbamoyl)amino]cyclohexyl]oxy)benzamide
-
 Gallus gallus
3.3.2.10 N-methyl-4-[[4-([[4-(trifluoromethoxy)phenyl]carbamoyl]amino)cyclohexyl]oxy]benzamide
-
 Gallus gallus
3.3.2.10 N-[4-(4-methoxyphenoxy)cyclohexyl]-N'-(tricyclo[3.3.1.13,7]dec-1-yl)methanediamine
-
 Gallus gallus
3.3.2.10 trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid
-
 Gallus gallus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.3.2.10 0.0015
-
 (3-phenyl-oxiranyl)-acetic acid cyano-(6-methoxy-naphthalen-2-yl)-methyl ester at pH 7.4 and 37°C Gallus gallus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.10 soluble
-
 Gallus gallus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.3.2.10 styrene oxide + H2O Gallus gallus
-
 styrene glycol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.10 Gallus gallus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.3.2.10 liver
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.10 (3-phenyl-oxiranyl)-acetic acid cyano-(6-methoxy-naphthalen-2-yl)-methyl ester + H2O
-
 Gallus gallus ?
-
 ?
3.3.2.10 styrene oxide + H2O
-
 Gallus gallus styrene glycol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.3.2.10 SEH
-
 Gallus gallus