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Literature summary extracted from

  • Harmon, S.D.; Fang, X.; Kaduce, T.L.; Hu, S.; Raj Gopal, V.; Falck, J.R.; Spector, A.A.
    Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production (2006), Prostaglandins Leukot. Essent. Fatty Acids, 75, 169-177.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.79 docosahexaenoic acid inhibitory to reaction of arachidonic acid Homo sapiens
1.14.14.79 eicosapentaenoic acid inhibitory to reaction of arachidonic acid Homo sapiens
1.14.14.79 omega-3 docosapentaenoic acid inhibitory to reaction of arachidonic acid Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.79 Homo sapiens Q08477
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.79 arachidonic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 20-hydroxyarachidonic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.79 docosapentaenoic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens 22-hydroxydocosapentaenoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.79 eicosapentaenoic acid + NADPH + H+ + O2
-
 Homo sapiens 20-hydroxyeicosapentaenoic acid + NADP+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.79 CYP4F3B
-
 Homo sapiens