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Literature summary extracted from

  • Matsuba, Y.; Nguyen, T.T.; Wiegert, K.; Falara, V.; Gonzales-Vigil, E.; Leong, B.; Schaefer, P.; Kudrna, D.; Wing, R.A.; Bolger, A.M.; Usadel, B.; Tissier, A.; Fernie, A.R.; Barry, C.S.; Pichersky, E.
    Evolution of a complex locus for terpene biosynthesis in Solanum (2013), Plant Cell, 25, 2022-2036.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.1.133 gene CPS2, located in a gene cluster on chromosome 8, DNA and amino acid sequence determination and analysis, phylogenetic analysis, genetic organization Solanum lycopersicum
4.2.1.133 gene CPS2, located in a gene cluster on chromosome 8, DNA and amino acid sequence determination and analysis, phylogenetic analysis, genetic organization Solanum habrochaites
4.2.1.133 gene Nt-CPS2, located in a gene cluster on chromosome 8, DNA and amino acid sequence determination and analysis, phylogenetic analysis, genetic organization Nicotiana tabacum

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.133 Nicotiana tabacum G3CCC0
-
-
4.2.1.133 Solanum habrochaites
-
 encodes a gene CPS2 orthologue, encoding for copal-8-ol diphosphate synthase, CLS, in other Solanum sp., but which here encodes a nonfunctional protein
-
4.2.1.133 Solanum lycopersicum
-
 encodes a gene CPS2 orthologue, encoding for copal-8-ol diphosphate synthase, CLS, in other Solanum sp., but which here encodes a nonfunctional protein
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.133 geranylgeranyl diphosphate + H2O
-
 Nicotiana tabacum (13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate i.e. copal-8-ol diphosphate ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.133 CLS
-
 Nicotiana tabacum
4.2.1.133 copal-8-ol diphosphate synthase
-
 Nicotiana tabacum
4.2.1.133 Nt-CPS2
-
 Nicotiana tabacum

General Information

EC Number General Information Comment Organism
4.2.1.133 evolution the Solanaceae functional gene cluster evolved by duplication and divergence of TPS genes, together with alterations in substrate specificity to utilize cis-prenyl diphosphates and through the acquisition of CPT genes Solanum lycopersicum
4.2.1.133 evolution the Solanaceae functional gene cluster evolved by duplication and divergence of TPS genes, together with alterations in substrate specificity to utilize cis-prenyl diphosphates and through the acquisition of CPT genes Solanum habrochaites
4.2.1.133 evolution the Solanaceae functional gene cluster evolved by duplication and divergence of TPS genes, together with alterations in substrate specificity to utilize cis-prenyl diphosphates and through the acquisition of CPT genes Nicotiana tabacum
4.2.1.133 metabolism copal-8-ol diphosphate, which is made from the all-trans geranylgeranyl diphosphate by copal-8-ol diphosphate synthase Nt-CPS2, is the substrate for Z-abienol synthase Nicotiana tabacum