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Literature summary extracted from

  • Corea, O.R.; Bedgar, D.L.; Davin, L.B.; Lewis, N.G.
    The arogenate dehydratase gene family: towards understanding differential regulation of carbon flux through phenylalanine into primary versus secondary metabolic pathways (2012), Phytochemistry, 82, 22-37.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.2.1.91 additional information homozygous T-DNA insertion lines are generated for five of the six ADT isozymes and used to generate double, triple, and quadruple knockout mutants in different combinations, regulation phenotypes,overview Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.2.1.91 chloroplast
-
Arabidopsis thaliana 9507
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.91 L-arogenate Arabidopsis thaliana
-
L-phenylalanine + H2O + CO2
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.91 Arabidopsis thaliana
-
six isozymes encoded by genes adt1-adt6
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.91 leaf
-
Arabidopsis thaliana
-
4.2.1.91 additional information L-Phe/Tyr and general amino acid pools development during weeks in tissues of isozyme knockout mutants compared to the wild-type enzyme, overview Arabidopsis thaliana
-
4.2.1.91 root
-
Arabidopsis thaliana
-
4.2.1.91 stem
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.91 L-arogenate
-
Arabidopsis thaliana L-phenylalanine + H2O + CO2
-
?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.91 AdT
-
Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
4.2.1.91 physiological function the enzyme is required for biosynthesis of L-phenylalanine. Specific ADTs are differentially regulated so as to control Phe biosynthesis for protein synthesis versus its much more massive deployment for phenylpropanoid metabolism, overview Arabidopsis thaliana