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Literature summary extracted from

  • Kime, L.; Clarke, J.E.; Romero A, D.; Grasby, J.A.; McDowall, K.J.
    Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry (2014), Nucleic Acids Res., 42, 4577-4589.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
3.1.26.12 T170V the mutant can cleave a 5'-triphosphorylated transcript efficiently at E3 or E5, but not both Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.26.12 RNA + H2O Escherichia coli
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.26.12 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.26.12 RNA + H2O
-
 Escherichia coli ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.26.12 RNase E
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
3.1.26.12 metabolism direct entry by RNase E has a major role in bacterial RNA metabolism. Direct entry is mediated by specific unpaired regions that are adjacent to, but not contiguous with, segments cleaved by RNase E. A 5'-monophosphate is not required to activate the catalytic step Escherichia coli