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Literature summary extracted from

  • Moore, S.J.; Mayer, M.J.; Biedendieck, R.; Deery, E.; Warren, M.J.
    Towards a cell factory for vitamin B12 production in Bacillus megaterium: bypassing of the cobalamin riboswitch control elements (2014), New Biotechnol., 31, 553-561.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.99.1.3 sirohydrochlorin + Co2+ Priestia megaterium
-
 cobalt-sirohydrochlorin + H+
-
 ?
4.99.1.3 sirohydrochlorin + Co2+ Priestia megaterium DSM 319
-
 cobalt-sirohydrochlorin + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.99.1.3 Priestia megaterium
-
-
-
4.99.1.3 Priestia megaterium DSM 319
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.99.1.3 sirohydrochlorin + Co2+
-
 Priestia megaterium cobalt-sirohydrochlorin + H+
-
 ?
4.99.1.3 sirohydrochlorin + Co2+
-
 Priestia megaterium DSM 319 cobalt-sirohydrochlorin + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.99.1.3 CbiX
-
 Priestia megaterium
4.99.1.3 cobaltochelatase
-
 Priestia megaterium

Expression

EC Number Organism Comment Expression
4.99.1.3 Priestia megaterium 10 nM exogenous cobalt decreases the levels of the enzyme 13fold down