BRENDA - Enzyme Database show

Molecular docking studies of disubstituted diaryl diselenides as mammalian delta-aminolevulinic acid dehydratase enzyme inhibitors

Saraiva, R.A.; Bueno, D.C.; Nogara, P.A.; Rocha, J.B.; J. Toxicol. Environ. Health A 75, 1012-1022 (2012)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.24
bis(4-chlorophenyl)diselenide
-
Homo sapiens
4.2.1.24
bis(4-methoxyphenyl)diselenide
-
Homo sapiens
4.2.1.24
bis[3-(trifluoromethyl)phenyl]diselenide
-
Homo sapiens
4.2.1.24
diphenyl diselenide
-
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.24
5-aminolevulinate
Homo sapiens
-
porphobilinogen + H2O
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.24
Homo sapiens
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.24
5-aminolevulinate
-
730290
Homo sapiens
porphobilinogen + H2O
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.24
bis(4-chlorophenyl)diselenide
-
Homo sapiens
4.2.1.24
bis(4-methoxyphenyl)diselenide
-
Homo sapiens
4.2.1.24
bis[3-(trifluoromethyl)phenyl]diselenide
-
Homo sapiens
4.2.1.24
diphenyl diselenide
-
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.24
5-aminolevulinate
Homo sapiens
-
porphobilinogen + H2O
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.24
5-aminolevulinate
-
730290
Homo sapiens
porphobilinogen + H2O
-
-
-
?