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Literature summary extracted from

  • Ghisaidoobe, A.T.; van den Berg, R.J.; Butt, S.S.; Strijland, A.; Donker-Koopman, W.E.; Scheij, S.; van den Nieuwendijk, A.M.; Koomen, G.J.; van Loevezijn, A.; Leemhuis, M.; Wennekes, T.; van der Stelt, M.; van der Marel, G.A.; van Boeckel, C.A.; Aerts, J.M.; Overkleeft, H.S.
    Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors (2014), J. Med. Chem., 57, 9096-9104.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.80 (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol i.e. miglitol Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-(5-[[3',5'-bis(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-(5-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-(5-[[4-(2-fluoropyridin-4-yl)phenyl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-(5-[[4-(2H-1,3-benzodioxol-5-yl)phenyl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-(5-[[4-(6-fluoropyridin-3-yl)phenyl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol i.e. miglustat or Zavesca Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-(hexyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-([(3R,10S,13S,17R)-10,13-dimethyl-17-[(2S)-7-methyloctan-2-yl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(1R)-1-([1,1'-biphenyl]-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(1S)-1-([1,1'-biphenyl]-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(2'-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(2-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(3'-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(3-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(4'-chloro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(4'-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(4,8-dihydropyren-1-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[(5,8-dihydronaphthalen-2-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-2-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-3-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-((adamantylmethoxy)hexyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-(adamantylmethoxy)pentyl)piperidine-3,4,5-triol i.e. AMP-DNM Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,10-trimethylundeca-2,6,9-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(2,3,4,5-tetrahydro-1,6-benzodioxocin-8-yl)phenyl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-3-yl)phenyl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-4-yl)phenyl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyrimidin-5-yl)phenyl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(adamantylhexyl)hexyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(adamantylhept-6-en-1-yl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(adamantylhexyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methoxy[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methyl[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methoxy[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methyl[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methoxy[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methyl[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5-phenylpyridin-2-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(phenanthren-9-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-(hexyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-([(3R,10S,13S,17R)-10,13-dimethyl-17-[(2S)-7-methyloctan-2-yl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-trio
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[(1R)-1-([1,1'-biphenyl]-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[(1S)-1-([1,1'-biphenyl]-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[(2-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[(3-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[(4,8-dihydropyren-1-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[(5,8-dihydronaphthalen-2-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-2-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-3-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-(adamantylmethoxy)pentyl)piperidine-3,4,5-triol i.e. ido-AMP-DNM Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,10-trimethylundeca-2,6,9-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(adamantylmethoxy)hexyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(6-adamantyloxyhexyl)piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-adamantylhexylpiperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[(6Z)-7-adamantylhept-6-en-1-yl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(phenanthren-9-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
2.4.1.80 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl][1,1'-biphenyl]-2-carbonitrile
-
 Homo sapiens
2.4.1.80 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl][1,1'-biphenyl]-3-carbonitrile
-
 Homo sapiens
2.4.1.80 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl][1,1'-biphenyl]-4-carbonitrile
-
 Homo sapiens
2.4.1.80 additional information identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors, synthesis of a series of D-gluco- and L-ido-configured iminosugars N-modified with a variety of hydrophobic functional groups and of a series of biphenyl-substituted iminosugars of both configurations (D-gluco and L-ido), overview. Iminosugars featuring N-pentyloxymethylaryl substituents are considerably more potent inhibitors of glucosylceramide synthase than their aliphatic counterparts. Biphenyl-substituted L-ido-configured deoxynojirimycin derivatives are selective for glucosylceramidase and the nonlysosomal glucosylceramidase Homo sapiens
2.4.1.80 N-adamantyl-6-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
-
 Homo sapiens
2.4.1.80 N-adamantyl-6-[(2S,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-(5-[[3',5'-bis(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-(5-[[4-(1,3-benzodioxol-5-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-(5-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-(5-[[4-(2-fluoropyridin-4-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-(5-[[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-(5-[[4-(6-fluoropyridin-3-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-(hexyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(2'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(3'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholestan-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(4'-chlorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-1-[5-[(4'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4'-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-3-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-4-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyrimidin-5-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(4,6,8a,10c-tetrahydropyren-1-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5-phenylpyridin-2-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5R)-octahydro-1H-2,5-methanoinden-6-ylmethoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3S,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2R,3S,4R,5S)-2-(hydroxymethyl)-1-[5-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(8a,10c-dihydropyren-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-(hexyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[(5Z)-6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hex-5-en-1-yl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(1R,5S)-tricyclo[3.3.1.13,7]dec-2-ylmethoxy]pentyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3S)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
-
 Homo sapiens
3.2.1.45 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-2-carbonitrile
-
 Homo sapiens
3.2.1.45 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-3-carbonitrile
-
 Homo sapiens
3.2.1.45 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-4-carbonitrile
-
 Homo sapiens
3.2.1.45 miglitol
-
 Homo sapiens
3.2.1.45 miglustat
-
 Homo sapiens
3.2.1.45 N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
-
 Homo sapiens
3.2.1.45 N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2S,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
-
 Homo sapiens
3.2.1.45 N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.80 Homo sapiens Q16739
-
-
3.2.1.45 Homo sapiens P04062
-
-
3.2.1.45 Homo sapiens Q9HCG7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.45 glucosylceramide + H2O
-
 Homo sapiens beta-D-glucose + ceramide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.80 GCS
-
 Homo sapiens
2.4.1.80 glucosylceramide synthase
-
 Homo sapiens
3.2.1.45 acid glucosylceramidase
-
 Homo sapiens
3.2.1.45 GBA1
-
 Homo sapiens
3.2.1.45 GBA2
-
 Homo sapiens
3.2.1.45 neutral glucosylceramidase
-
 Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.4.1.80 0.0000025
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(2-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000003
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(5,8-dihydronaphthalen-2-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000003
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4,8-dihydropyren-1-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000003
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(5,8-dihydronaphthalen-2-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000003
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(4,8-dihydropyren-1-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000003
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.000003
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.000005
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000008
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000015
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00002
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.00002
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[3',5'-bis(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00002
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methyl[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methoxy[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3'-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-chloro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2H-1,3-benzodioxol-5-yl)phenyl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(2,3,4,5-tetrahydro-1,6-benzodioxocin-8-yl)phenyl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.000025
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-2-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00003
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1R)-1-([1,1'-biphenyl]-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00004
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00004
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1S)-1-([1,1'-biphenyl]-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00005
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00005
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methoxy[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
2.4.1.80 0.00005
-
 pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl][1,1'-biphenyl]-3-carbonitrile
2.4.1.80 0.00005
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-2-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00006
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00006
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1R)-1-([1,1'-biphenyl]-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00007
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00007
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1S)-1-([1,1'-biphenyl]-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00007
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-3-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000075
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2'-fluoro[1,1'-biphenyl]-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.000075
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-3-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00008
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(6-adamantyloxyhexyl)piperidine-3,4,5-triol
2.4.1.80 0.0001
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-(adamantylmethoxy)pentyl)piperidine-3,4,5-triol
2.4.1.80 0.0001
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methyl[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
2.4.1.80 0.0001
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methyl[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
2.4.1.80 0.00015
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methoxy[1,1'-biphenyl]-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
2.4.1.80 0.00015
-
 pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl][1,1'-biphenyl]-4-carbonitrile
2.4.1.80 0.00015
-
 pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl][1,1'-biphenyl]-2-carbonitrile
2.4.1.80 0.00015
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2-fluoropyridin-4-yl)phenyl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.0002
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.0002
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5-phenylpyridin-2-yl)methoxy]pentyl]piperidine-3,4,5-triol
2.4.1.80 0.0002
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-(adamantylmethoxy)pentyl)piperidine-3,4,5-triol
2.4.1.80 0.00025
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(adamantylmethoxy)hexyl)piperidine-3,4,5-triol
2.4.1.80 0.0003
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-((adamantylmethoxy)hexyl)piperidine-3,4,5-triol
2.4.1.80 0.0003
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(adamantylhexyl)hexyl)piperidine-3,4,5-triol
2.4.1.80 0.0004
-
 pH and temperature not specified in the publication Homo sapiens N-adamantyl-6-[(2S,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
2.4.1.80 0.0005
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00075
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.00075
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(6-fluoropyridin-3-yl)phenyl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.001
-
 pH and temperature not specified in the publication Homo sapiens N-adamantyl-6-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
2.4.1.80 0.001
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-([(3R,10S,13S,17R)-10,13-dimethyl-17-[(2S)-7-methyloctan-2-yl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.001
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-([(3R,10S,13S,17R)-10,13-dimethyl-17-[(2S)-7-methyloctan-2-yl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-trio
2.4.1.80 0.00125
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[([1,1'-biphenyl]-4-yl)methoxy]-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
2.4.1.80 0.002
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-4-yl)phenyl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.002
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-3-yl)phenyl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.002
-
 pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyrimidin-5-yl)phenyl]methoxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.0025
-
 pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,10-trimethylundeca-2,6,9-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.02
-
 above, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(adamantylhept-6-en-1-yl)piperidine-3,4,5-triol
2.4.1.80 0.02
-
 above, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(adamantylhexyl)piperidine-3,4,5-triol
2.4.1.80 0.02
-
 above, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,10-trimethylundeca-2,6,9-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
2.4.1.80 0.02
-
 above, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(phenanthren-9-yl)methoxy]pentyl]piperidine-3,4,5-triol
2.4.1.80 0.02
-
 above, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[(6Z)-7-adamantylhept-6-en-1-yl]piperidine-3,4,5-triol
2.4.1.80 0.02
-
 above, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-adamantylhexylpiperidine-3,4,5-triol
2.4.1.80 0.02
-
 above, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(phenanthren-9-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.00000008
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00000008
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00000008
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.0000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.0000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.00000012
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.0000004
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0000005
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.0000006
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5R)-octahydro-1H-2,5-methanoinden-6-ylmethoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(8a,10c-dihydropyren-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-2-(hydroxymethyl)-1-[5-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(1R,5S)-tricyclo[3.3.1.13,7]dec-2-ylmethoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-3-carbonitrile
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-chlorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(1,3-benzodioxol-5-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0000025
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(4,6,8a,10c-tetrahydropyren-1-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-4-carbonitrile
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5-phenylpyridin-2-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000004
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000004
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2-fluoropyridin-4-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000005
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000005
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholestan-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000005
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-2-carbonitrile
3.2.1.45 0.000005
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(6-fluoropyridin-3-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000006
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000008
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[(5Z)-6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hex-5-en-1-yl]piperidine-3,4,5-triol
3.2.1.45 0.000009
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
3.2.1.45 0.00001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
3.2.1.45 0.00001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.00001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4'-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.00001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-4-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.00001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-3-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.00001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000015
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2S,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
3.2.1.45 0.000015
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[3',5'-bis(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.000015
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3S)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
3.2.1.45 0.00002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.000025
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyrimidin-5-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.00003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00006
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
3.2.1.45 0.00007
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.0001
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
3.2.1.45 0.0001
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
3.2.1.45 0.0001
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.0001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.0001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.0001
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.000125
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0002
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0002
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.0002
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-2-(hydroxymethyl)-1-[5-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.0002
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.00025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.00025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.00025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00025
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0003
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0003
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0003
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0003
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0003
-
 isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.00035
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-4-carbonitrile
3.2.1.45 0.0004
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5R)-octahydro-1H-2,5-methanoinden-6-ylmethoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.0004
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0004
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0005
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
3.2.1.45 0.0005
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0005
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholestan-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0005
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(4,6,8a,10c-tetrahydropyren-1-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.0005
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-chlorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0005
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(1,3-benzodioxol-5-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0006
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.0006
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-2-carbonitrile
3.2.1.45 0.0006
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0007
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-3-carbonitrile
3.2.1.45 0.0008
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4'-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.0008
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[3',5'-bis(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.001
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.00125
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0015
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0015
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5-phenylpyridin-2-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.002
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
3.2.1.45 0.002
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-4-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.002
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2-fluoropyridin-4-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.0025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.0025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.0025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.003
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.003
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-3-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.003
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(6-fluoropyridin-3-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.005
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
3.2.1.45 0.005
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.006
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.006
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.008
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.01
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.01
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(1R,5S)-tricyclo[3.3.1.13,7]dec-2-ylmethoxy]pentyl]piperidine-3,4,5-triol
3.2.1.45 0.01
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.01
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyrimidin-5-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.01
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.01
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.012
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[(5Z)-6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hex-5-en-1-yl]piperidine-3,4,5-triol
3.2.1.45 0.0125
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.015
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.015
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(8a,10c-dihydropyren-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.015
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.02
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.02
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.025
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3S)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
3.2.1.45 0.04
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2S,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
3.2.1.45 0.05
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
3.2.1.45 0.05
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
3.2.1.45 0.06
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.2
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.32
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.4
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.5
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
3.2.1.45 0.6
-
 isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol