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Literature summary extracted from

  • Reichardt, N.; Duncan, S.H.; Young, P.; Belenguer, A.; McWilliam Leitch, C.; Scott, K.P.; Flint, H.J.; Louis, P.
    Phylogenetic distribution of three pathways for propionate production within the human gut microbiota (2014), ISME J., 8, 1323-1335.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.54 (R)-lactoyl-CoA Megasphaera elsdenii
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridium sp.
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridium botulinum
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridioides difficile
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA [Clostridium] symbiosum
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridium novyi
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Coprococcus catus
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Anaerotignum propionicum
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA butyrate-producing bacterium SS3/4
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Enterocloster asparagiformis
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridium novyi NT
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Coprococcus catus GD/7
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA [Clostridium] symbiosum WAL-14163
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridioides difficile 630
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Enterocloster asparagiformis DSM 15981
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Anaerotignum propionicum DSM 1682
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridium sp. M62/1
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridium sp. MSTE9 (cluster XIVb)
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Megasphaera elsdenii LC1 DSM 20460T
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridium botulinum C Eklund
-
 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA Clostridium botulinum A2
-
 acryloyl-CoA + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.54 Anaerotignum propionicum G3KIM4 subunit alpha
-
4.2.1.54 Anaerotignum propionicum DSM 1682 G3KIM4 subunit alpha
-
4.2.1.54 butyrate-producing bacterium SS3/4
-
-
-
4.2.1.54 Clostridioides difficile
-
-
-
4.2.1.54 Clostridioides difficile 630
-
-
-
4.2.1.54 Clostridium botulinum
-
-
-
4.2.1.54 Clostridium botulinum A2
-
-
-
4.2.1.54 Clostridium botulinum C Eklund
-
-
-
4.2.1.54 Clostridium novyi
-
-
-
4.2.1.54 Clostridium novyi NT
-
-
-
4.2.1.54 Clostridium sp.
-
-
-
4.2.1.54 Clostridium sp. M62/1
-
-
-
4.2.1.54 Clostridium sp. MSTE9 (cluster XIVb)
-
-
-
4.2.1.54 Coprococcus catus
-
-
-
4.2.1.54 Coprococcus catus GD/7
-
-
-
4.2.1.54 Enterocloster asparagiformis
-
-
-
4.2.1.54 Enterocloster asparagiformis DSM 15981
-
-
-
4.2.1.54 Megasphaera elsdenii
-
-
-
4.2.1.54 Megasphaera elsdenii LC1 DSM 20460T
-
-
-
4.2.1.54 [Clostridium] symbiosum
-
-
-
4.2.1.54 [Clostridium] symbiosum WAL-14163
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.54 (R)-lactoyl-CoA
-
 Megasphaera elsdenii acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridium sp. acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridium botulinum acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridioides difficile acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 [Clostridium] symbiosum acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridium novyi acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Coprococcus catus acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Anaerotignum propionicum acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 butyrate-producing bacterium SS3/4 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Enterocloster asparagiformis acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridium novyi NT acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Coprococcus catus GD/7 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 [Clostridium] symbiosum WAL-14163 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridioides difficile 630 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Enterocloster asparagiformis DSM 15981 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Anaerotignum propionicum DSM 1682 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridium sp. M62/1 acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridium sp. MSTE9 (cluster XIVb) acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Megasphaera elsdenii LC1 DSM 20460T acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridium botulinum C Eklund acryloyl-CoA + H2O
-
 ?
4.2.1.54 (R)-lactoyl-CoA
-
 Clostridium botulinum A2 acryloyl-CoA + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 Megasphaera elsdenii
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 Clostridium sp.
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 Clostridium botulinum
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 Clostridioides difficile
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 [Clostridium] symbiosum
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 Clostridium novyi
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 Coprococcus catus
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 Anaerotignum propionicum
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 butyrate-producing bacterium SS3/4
4.2.1.54 lactoyl-CoA dehydratase subunit alpha
-
 Enterocloster asparagiformis
4.2.1.54 lcdA
-
 Megasphaera elsdenii
4.2.1.54 lcdA
-
 Clostridium sp.
4.2.1.54 lcdA
-
 Clostridium botulinum
4.2.1.54 lcdA
-
 Clostridioides difficile
4.2.1.54 lcdA
-
 [Clostridium] symbiosum
4.2.1.54 lcdA
-
 Clostridium novyi
4.2.1.54 lcdA
-
 Coprococcus catus
4.2.1.54 lcdA
-
 Anaerotignum propionicum
4.2.1.54 lcdA
-
 butyrate-producing bacterium SS3/4
4.2.1.54 lcdA
-
 Enterocloster asparagiformis