BRENDA - Enzyme Database

The enolase of Borrelia burgdorferi is a plasminogen receptor released in outer membrane vesicles

Toledo, A.; Coleman, J.L.; Kuhlow, C.J.; Crowley, J.T.; Benach, J.L.; Infect. Immun. 80, 359-368 (2012)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
4.2.1.11
expressed in Escherichia coli Rosetta (DE3) cells
Borreliella burgdorferi
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.2.1.11
additional information
the enzyme is not exposed on the cell surface
Borreliella burgdorferi
-
-
4.2.1.11
vesicle
outer membrane vesicle
Borreliella burgdorferi
31982
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.2.1.11
47000
-
x * 47000, calculated from amino acid sequence
Borreliella burgdorferi
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.11
2-phospho-D-glycerate
Borreliella burgdorferi
-
phosphoenolpyruvate + H2O
-
-
?
4.2.1.11
2-phospho-D-glycerate
Borreliella burgdorferi B31
-
phosphoenolpyruvate + H2O
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.11
Borreliella burgdorferi
-
-
-
4.2.1.11
Borreliella burgdorferi B31
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
4.2.1.11
His-Trap column chromatography
Borreliella burgdorferi
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
729820
Borreliella burgdorferi
phosphoenolpyruvate + H2O
-
-
-
?
4.2.1.11
2-phospho-D-glycerate
-
729820
Borreliella burgdorferi B31
phosphoenolpyruvate + H2O
-
-
-
?
4.2.1.11
additional information
enolase binds plasminogen in a lysine-dependent manner but not through ionic interactions
729820
Borreliella burgdorferi
?
-
-
-
-
4.2.1.11
additional information
enolase binds plasminogen in a lysine-dependent manner but not through ionic interactions
729820
Borreliella burgdorferi B31
?
-
-
-
-
Subunits
EC Number
Subunits
Commentary
Organism
4.2.1.11
?
x * 47000, calculated from amino acid sequence
Borreliella burgdorferi
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
4.2.1.11
expressed in Escherichia coli Rosetta (DE3) cells
Borreliella burgdorferi
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.2.1.11
additional information
the enzyme is not exposed on the cell surface
Borreliella burgdorferi
-
-
4.2.1.11
vesicle
outer membrane vesicle
Borreliella burgdorferi
31982
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.2.1.11
47000
-
x * 47000, calculated from amino acid sequence
Borreliella burgdorferi
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.11
2-phospho-D-glycerate
Borreliella burgdorferi
-
phosphoenolpyruvate + H2O
-
-
?
4.2.1.11
2-phospho-D-glycerate
Borreliella burgdorferi B31
-
phosphoenolpyruvate + H2O
-
-
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
4.2.1.11
His-Trap column chromatography
Borreliella burgdorferi
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
729820
Borreliella burgdorferi
phosphoenolpyruvate + H2O
-
-
-
?
4.2.1.11
2-phospho-D-glycerate
-
729820
Borreliella burgdorferi B31
phosphoenolpyruvate + H2O
-
-
-
?
4.2.1.11
additional information
enolase binds plasminogen in a lysine-dependent manner but not through ionic interactions
729820
Borreliella burgdorferi
?
-
-
-
-
4.2.1.11
additional information
enolase binds plasminogen in a lysine-dependent manner but not through ionic interactions
729820
Borreliella burgdorferi B31
?
-
-
-
-
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
4.2.1.11
?
x * 47000, calculated from amino acid sequence
Borreliella burgdorferi