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Literature summary extracted from
- Neohesperidin dihydrochalcone: presentation of a small molecule activator of mammalian alpha-amylase as an allosteric effector (2013), FEBS Lett., 587, 652-658.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.1.1 | neohesperidin dihydrochalcone | up to 3fold activation at 4.8 mM | Sus scrofa |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.1 | Sus scrofa | P00690 | isoform Amy2 | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.1.1 | pancreas | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.1 | starch + H2O | - |
Sus scrofa | ? | - |
? | |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.2.1.1 | 0.017 | - |
starch | pH 7.2, 42°C | Sus scrofa | |
| 3.2.1.1 | 0.022 | - |
starch | presence of 0.4 mM neohesperidin dihydrochalcone, pH 7.2, 42°C | Sus scrofa | |
| 3.2.1.1 | 0.035 | - |
starch | presence of 2.4 mM neohesperidin dihydrochalcone, pH 7.2, 42°C | Sus scrofa | |
| 3.2.1.1 | 0.04 | - |
starch | presence of 4.8 mM neohesperidin dihydrochalcone, pH 7.2, 42°C | Sus scrofa | |
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Release 2023.1 (January 2023)
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