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Literature summary extracted from

  • Wichelecki, D.; Vendiola, J.; Jones, A.; Al-Obaidi, N.; Almo, S.; Gerlt, J.
    Investigating the physiological roles of low-efficiency D-mannonate and D-gluconate dehydratases in the enolase superfamily: Pathways for the catabolism of L-gulonate and L-idonate (2014), Biochemistry, 53, 5692-5699.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.380
-
 Halomonas elongata

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.380 L-gulonate + NAD+ Halomonas elongata the enzyme participates in a pathway for L-gulonate degradation D-fructuronate + NADH + H+
-
 ?
1.1.1.380 L-gulonate + NAD+ Halomonas elongata DSM 2581 the enzyme participates in a pathway for L-gulonate degradation D-fructuronate + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.380 Halomonas elongata E1V4Y1
-
-
1.1.1.380 Halomonas elongata DSM 2581 E1V4Y1
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.380
-
 Halomonas elongata

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.380 L-gulonate + NAD+
-
 Halomonas elongata D-fructuronate + NADH + H+
-
 ?
1.1.1.380 L-gulonate + NAD+ the enzyme participates in a pathway for L-gulonate degradation Halomonas elongata D-fructuronate + NADH + H+
-
 ?
1.1.1.380 L-gulonate + NAD+
-
 Halomonas elongata DSM 2581 D-fructuronate + NADH + H+
-
 ?
1.1.1.380 L-gulonate + NAD+ the enzyme participates in a pathway for L-gulonate degradation Halomonas elongata DSM 2581 D-fructuronate + NADH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.380 HeGulDH
-
 Halomonas elongata

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.380 25
-
 assay at Halomonas elongata

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.1.1.380 1.8
-
 L-gulonate pH 7.9, 25°C Halomonas elongata

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.380 7.9
-
 assay at Halomonas elongata

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.380 NAD+
-
 Halomonas elongata

General Information

EC Number General Information Comment Organism
1.1.1.380 metabolism the enzyme participates in a pathway for L-gulonate degradation Halomonas elongata

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
1.1.1.380 0.6
-
 L-gulonate pH 7.9, 25°C Halomonas elongata