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Literature summary extracted from

  • Song, H.S.; Choi, M.Y.; Ko, M.S.; Jeong, J.M.; Kim, Y.H.; Jang, B.H.; Sung, J.H.; Kim, M.G.; Whang, W.K.; Sim, S.S.
    Competitive inhibition of cytosolic Ca2+-dependent phospholipase A2 by acteoside in RBL-2H3 cells (2012), Arch. Pharm. Res., 35, 905-910.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.4 acteoside phenylethanoid glycoside isolated from Clerodendron trichotomum Thunberg, competitive. Acts on cytosolic Ca2+-dependent phospholipase A2 rather than secretory phospholipase A2 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.4 cytosol
-
 Rattus norvegicus 5829
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 RBL-2H3 cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphocholine + H2O
-
 Rattus norvegicus 1-palmitoyl-sn-glycero-3-phosphorylcholine + arachidonic acid
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.4 0.0059
-
 acteoside pH 8.5, 22°C, crude protein preparation Rattus norvegicus