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Literature summary extracted from
- Subcellular localization of 3alpha,7alpha-dihydroxy- and 3alpha,7alpha,12alpha-trihydroxy-5beta-cholastanoyl-coenzyme A ligase(s) in rat liver (1988), J. Lipid Res., 29, 997-1004.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 6.2.1.7 | bovine serum albumin | activation | Rattus norvegicus | |
| 6.2.1.7 | dithiothreitol | activation | Rattus norvegicus |  |
| 6.2.1.7 | Triton X-100 | activation | Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 6.2.1.7 | endoplasmic reticulum | - |
Rattus norvegicus | 5783 | - |
| 6.2.1.28 | endoplasmic reticulum | - |
Rattus norvegicus | 5783 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 6.2.1.7 | Mg2+ | required | Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 6.2.1.7 | ATP + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate + CoA | Rattus norvegicus | - |
AMP + diphosphate + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA | - |
? | |
| 6.2.1.28 | ATP + 3alpha,7alpha-dihydroxy-5beta-cholestanate + CoA | Rattus norvegicus | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 6.2.1.7 | Rattus norvegicus | - |
- |
- |
| 6.2.1.28 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 6.2.1.7 | liver | - |
Rattus norvegicus | - |
| 6.2.1.28 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 6.2.1.7 | 0.0018 | - |
activity of microsomal extraxt | Rattus norvegicus |
| 6.2.1.28 | 0.0015 | - |
activity of microsomal fraction | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 6.2.1.7 | ATP + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate + CoA | - |
Rattus norvegicus | AMP + diphosphate + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA | - |
? | |
| 6.2.1.28 | ATP + 3alpha,7alpha-dihydroxy-5beta-cholestanate + CoA | - |
Rattus norvegicus | AMP + diphosphate + 3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA | - |
? | |
| 6.2.1.28 | ATP + 3alpha,7alpha-dihydroxy-5beta-cholestanate + CoA | - |
Rattus norvegicus | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 6.2.1.7 | 7.7 | - |
- |
Rattus norvegicus |
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