EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.22 | S-adenosyl-L-methionine | the addition of S-adenosyl-L-methionine nearly doubles enzyme activity | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.2.1.22 | 55000 | - |
x * 55000, SDS-PAGE | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.22 | L-serine + L-homocysteine | Homo sapiens | - |
L-cystathionine + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.22 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.2.1.22 | peripheral blood mononuclear cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.22 | L-serine + L-homocysteine | - |
Homo sapiens | L-cystathionine + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.2.1.22 | ? | x * 55000, SDS-PAGE | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.1.22 | CBS | - |
Homo sapiens |
4.2.1.22 | cystathionine beta-synthase | - |
Homo sapiens |
EC Number | Organism | Comment | Expression |
---|---|---|---|
4.2.1.22 | Homo sapiens | protein level and activity increase with incubation time, upon stimulation, and similar to intracellular homocysteine, depending on intra- and extracellular homocysteine and glutathione concentrations | up |