Any feedback?
Literature summary extracted from
- Biochemical characterization and ligand-binding properties of trehalose-6-phosphate phosphatase from Mycobacterium tuberculosis (2013), Acta Biochim. Biophys. Sin., 45, 837-844.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.3.12 | expressed in Escherichia coli BL21(DE3) cells | Mycobacterium tuberculosis |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.12 | Mg2+ | required | Mycobacterium tuberculosis |  |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.12 | 46228 | - |
x * 46228, MALDI-TOF mass spectrometry | Mycobacterium tuberculosis |
| 3.1.3.12 | 46236 | - |
x * 46236, calculated from amino acid sequence | Mycobacterium tuberculosis |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.12 | trehalose 6-phosphate + H2O | Mycobacterium tuberculosis | - |
trehalose + phosphate | - |
? | |
| 3.1.3.12 | trehalose 6-phosphate + H2O | Mycobacterium tuberculosis ATCC 25618 | - |
trehalose + phosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.12 | Mycobacterium tuberculosis | - |
- |
- |
| 3.1.3.12 | Mycobacterium tuberculosis ATCC 25618 | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.3.12 | Ni-NTA affinity column chromatography and S200 gel filtration | Mycobacterium tuberculosis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.12 | trehalose 6-phosphate + H2O | - |
Mycobacterium tuberculosis | trehalose + phosphate | - |
? | |
| 3.1.3.12 | trehalose 6-phosphate + H2O | - |
Mycobacterium tuberculosis ATCC 25618 | trehalose + phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.3.12 | ? | x * 46228, MALDI-TOF mass spectrometry | Mycobacterium tuberculosis |
| 3.1.3.12 | ? | x * 46236, calculated from amino acid sequence | Mycobacterium tuberculosis |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.3.12 | TPP | - |
Mycobacterium tuberculosis |
| 3.1.3.12 | trehalose-6-phosphate phosphatase | - |
Mycobacterium tuberculosis |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.1.3.12 | physiological function | an essential enzyme for growth | Mycobacterium tuberculosis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
