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Literature summary extracted from

  • Settle, T.; Carro, M.D.; Falkenstein, E.; Radke, W.; Klandorf, H.
    The effects of allopurinol, uric acid, and inosine administration on xanthine oxidoreductase activity and uric acid concentrations in broilers (2012), Poult. Sci., 91, 2895-2903.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.1.4 allopurinol XOR activity in liver reduced by allopurinol treatment, no effect in kidney. Birds fed with inosine and allopurinol show lower total XOR activity in liver but no effect in kidney Gallus gallus

Organism

EC Number Organism UniProt Comment Textmining
1.17.1.4 Gallus gallus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.1.4 kidney
-
 Gallus gallus
-
1.17.1.4 liver XOR activity reduced by allopurinol treatment. Birds fed with inosine and allopurinol show lower total XOR activity in liver but no effect in kidney Gallus gallus
-
1.17.1.4 plasma
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.1.4 xanthine + NAD+ + H2O
-
 Gallus gallus urate + NADH
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.17.1.4 xanthine oxidoreductase
-
 Gallus gallus
1.17.1.4 XOR
-
 Gallus gallus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.17.1.4 41
-
 assay at Gallus gallus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.17.1.4 7.8
-
 assay at Gallus gallus