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Literature summary extracted from

  • Guo, F.; Zhou, W.; Zhang, J.; Xu, Q.; Deng, X.
    Effect of the citrus lycopene beta-cyclase transgene on carotenoid metabolism in transgenic tomato fruits (2012), PLoS ONE, 7, e32221.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
5.5.1.19 nutrition as tomato fruits are rich in beta-carotene precursors, there is a substantial interest in engineering carotenoid synthesis in tomato with a view to enhancing its beta-carotene content, through recombinant expression of the gene encoding lypoene beta-cyclase, for improving the human diet Citrus sp.

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.5.1.19 gene Lycb-1, constitutive heterologous expression in Solanum lycopersicum fruits. In the transgenic line, the downstream alpha-branch metabolic fluxes are repressed during the three developmental stages while alpha-carotene content increases in the ripe stage, the beta-carotene level of transformant increases 4.1fold, and the total carotenoid content increases by 30% in the fruits. The constitutive expression of Lycb-1 affects a number of pathways including the synthesis of fatty acids, flavonoids and phenylpropanoids, the degradation of limonene and pinene, starch and sucrose metabolism and photosynthesis. Carotenoids contents in transgenic fruits at different stages of ripening, overview Citrus sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.5.1.19 lycopene Citrus sp.
-
 beta-carotene
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.5.1.19 Citrus sp.
-
 gene Lycb-1
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.5.1.19 lycopene
-
 Citrus sp. beta-carotene
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.5.1.19 LYCB
-
 Citrus sp.

General Information

EC Number General Information Comment Organism
5.5.1.19 metabolism key enzyme for the synthesis of beta-carotene Citrus sp.
5.5.1.19 physiological function regulatory effect of Lycb-1 gene on plant carotenoid metabolism and fruit transcriptome, overview Citrus sp.