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Literature summary extracted from

  • Azzam, G.; Liu, J.L.
    Only one isoform of Drosophila melanogaster CTP synthase forms the cytoophidium (2013), PLoS Genet., 9, e1003256.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.4.2 expressed in Escherichia coli BL21(DE3) cells Drosophila melanogaster

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.3.4.2 cytoophidium CTP synthase isoform C forms the cytoophidium Drosophila melanogaster 97268
-
6.3.4.2 cytoplasm CTP synthase isoform B distributes diffusely in the cytoplasm Drosophila melanogaster 5737
-
6.3.4.2 nucleus CTP synthase isoform A localizes in the nucleus Drosophila melanogaster 5634
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.4.2 70000
-
 x * 70000, SDS-PAGE Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.4.2 ATP + UTP + L-glutamine Drosophila melanogaster
-
 ADP + phosphate + CTP + L-glutamate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.2 Drosophila melanogaster
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.4.2 Ni2+-IDA resin column chromatography Drosophila melanogaster

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.4.2 adult
-
 Drosophila melanogaster
-
6.3.4.2 embryo
-
 Drosophila melanogaster
-
6.3.4.2 larva
-
 Drosophila melanogaster
-
6.3.4.2 pupa
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.2 ATP + UTP + L-glutamine
-
 Drosophila melanogaster ADP + phosphate + CTP + L-glutamate
-
 ?

Subunits

EC Number Subunits Comment Organism
6.3.4.2 ? x * 70000, SDS-PAGE Drosophila melanogaster

Synonyms

EC Number Synonyms Comment Organism
6.3.4.2 CTP synthase
-
 Drosophila melanogaster
6.3.4.2 CTPsyn
-
 Drosophila melanogaster

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.4.2 ATP
-
 Drosophila melanogaster

General Information

EC Number General Information Comment Organism
6.3.4.2 malfunction mutations disrupting CTP synthase isoform C or isoform A expression results in cytoophidium disassembly Drosophila melanogaster