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Literature summary extracted from

  • Song, L.; Zhang, Y.; Li, S.; Hu, J.; Yin, W.; Chen, Y.; Hao, S.; Wang, B.; Wang, R.; Hu, Z.
    Identification of the substrate recognition region in the DELTA6-fatty acid and DELTA8-sphingolipid desaturase by fusion mutagenesis (2014), Planta, 239, 753-763.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.3 expressed in Saccharomyces cerevisiae strain InvSc1 Ribes nigrum
1.14.19.18 expressed in Saccharomyces cerevisiae Ribes nigrum
1.14.19.29 expressed in Saccharomyces cerevisiae strain InvSc1 Ribes nigrum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.19.18 membrane
-
 Ribes nigrum 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.29 (4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ Ribes nigrum 32.5% conversion rate (4R,8E)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O
-
 ?
1.14.19.29 (4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ Ribes nigrum 32.5% conversion rate (4R,8Z)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.3 Ribes nigrum
-
-
-
1.14.19.18 Ribes nigrum
-
-
-
1.14.19.29 Ribes nigrum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.3 alpha-linolenic acid + AH2 + O2
-
 Ribes nigrum octadecatetraenoic acid + A + 2 H2O
-
 ?
1.14.19.3 linoleic acid + AH2 + O2 14.4% conversion rate Ribes nigrum gamma-linolenic acid + A + H2O
-
 ?
1.14.19.18 C18-phytosphingosine + ferrocytochrome b5 + O2 + H+
-
 Ribes nigrum (8Z)-C18-phytosphingenine + (8E)-C18-phytosphingenine + ferricytochrome b5 + H2O
-
 ?
1.14.19.29 (4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ 32.5% conversion rate Ribes nigrum (4R,8E)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O
-
 ?
1.14.19.29 (4R)-4-hydroxysphinganine ceramide + ferrocytochrome b5 + O2 + H+ 32.5% conversion rate Ribes nigrum (4R,8Z)-4-hydroxysphing-8-enine ceramide + ferricytochrome b5 + H2O
-
 ?
1.14.19.29 additional information the enzyme has no DELTA6-desaturase activity Ribes nigrum ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.3 D6D
-
 Ribes nigrum
1.14.19.3 DELTA6-fatty acid desaturase
-
 Ribes nigrum
1.14.19.18 D8D
-
 Ribes nigrum
1.14.19.18 DELTA8-sphingolipid desaturase
-
 Ribes nigrum
1.14.19.29 D8A
-
 Ribes nigrum
1.14.19.29 D8D
-
 Ribes nigrum
1.14.19.29 DELTA8-sphingolipid desaturase
-
 Ribes nigrum

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.18 cytochrome b5
-
 Ribes nigrum
1.14.19.29 cytochrome b5
-
 Ribes nigrum