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Literature summary extracted from

  • Paulus, J.K.; Niehus, C.; Groth, G.
    Evolution of C4 phosphoenolpyruvate carboxylase: enhanced feedback inhibitor tolerance is determined by a single residue (2013), Mol. Plant, 6, 1996-1999.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.1.1.31 R884E the mutant is clearly less sensitive towards malate compared to the wild type enzyme Flaveria pringlei
4.1.1.31 R884Q the mutant is clearly less sensitive towards malate compared to the wild type enzyme Flaveria pringlei
4.1.1.31 R884S the mutant is clearly less sensitive towards malate compared to the wild type enzyme Flaveria pringlei

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.31 malate
-
Flaveria pringlei
4.1.1.31 malate
-
Flaveria trinervia

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.31 phosphoenolpyruvate + HCO3- Flaveria trinervia
-
phosphate + oxaloacetate
-
?
4.1.1.31 phosphoenolpyruvate + HCO3- Flaveria pringlei
-
phosphate + oxaloacetate
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.31 Flaveria pringlei Q01647
-
-
4.1.1.31 Flaveria trinervia
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.31 phosphoenolpyruvate + HCO3-
-
Flaveria trinervia phosphate + oxaloacetate
-
?
4.1.1.31 phosphoenolpyruvate + HCO3-
-
Flaveria pringlei phosphate + oxaloacetate
-
?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.31 PEPC
-
Flaveria trinervia
4.1.1.31 PEPC
-
Flaveria pringlei

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
4.1.1.31 0.0000026
-
wild type enzyme, pH and temperature not specified in the publication Flaveria pringlei malate
4.1.1.31 4.3
-
mutant enzyme R884Q, pH and temperature not specified in the publication Flaveria pringlei malate
4.1.1.31 6.6
-
mutant enzyme R884S, pH and temperature not specified in the publication Flaveria pringlei malate
4.1.1.31 8.7
-
wild type enzyme, pH and temperature not specified in the publication Flaveria trinervia malate
4.1.1.31 15.7
-
mutant enzyme R884E, pH and temperature not specified in the publication Flaveria pringlei malate