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Literature summary extracted from

  • da Silva, L.F.; Dias, C.V.; Cidade, L.C.; Mendes, J.S.; Pirovani, C.P.; Alvim, F.C.; Pereira, G.A.; Aragao, F.J.; Cascardo, J.C.; Costa, M.G.
    Expression of an oxalate decarboxylase impairs the necrotic effect induced by Nep1-like protein (NLP) of Moniliophthora perniciosa in transgenic tobacco (2011), Mol. Plant Microbe Interact., 24, 839-848.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.1.1.2 agriculture the enzyme represents a potentially source of resistance against oxalate- and Nep1-like protein-producing pathogens such as Moniliophthora perniciosa, the causal agent of witches' broom disease of cacao, Theobroma cacao Flammulina velutipes

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.2 transgenic overexpressionin Nicotiana tabacum plants. The transgenic plants contain less oxalic acid and more formic acid compared with the control plants and show enhanced resistance to cell death induced by exogenous oxalate and MpNEP2, a Nep1-like protein of the hemibiotrophic fungus Moniliophthora perniciosa. inhibition of reactive oxygen species formation in the transgenic plants inoculated with oxalate, MpNEP2, or a combination of both programmed cell death elicitors Flammulina velutipes

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.2 oxalate + H+ Flammulina velutipes
-
formate + CO2
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.2 Flammulina velutipes
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.2 oxalate + H+
-
Flammulina velutipes formate + CO2
-
?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.2 FvOXDC
-
Flammulina velutipes

General Information

EC Number General Information Comment Organism
4.1.1.2 additional information the enzyme is involved in resistance against oxalate- and Nep1-like protein-producing pathogens in plants. Oxalic acid and Nep1-like proteins are recognized as elicitors of programmed cell death in plants, which is crucial for the pathogenic success of necrotrophic plant pathogens and involves reactive oxygen species Flammulina velutipes